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Biomedical subjects

J C Townsend

Publications and source records attributed to J C Townsend.

65 records · Page 4Linked to original sources

Coronary heart disease index based on longitudinal electrocardiography.

A coronary heart disease index was developed from longitudinal ECG (LCG) tracings to serve as a cardiac health measure in studies of working and, essentially, asymptomatic populations, such as pilots and executives. For a given subject, the index consisted of a composite score based on the presence of LCG aberrations and weighted values previously assigned to them. The index was validated by correlating it with the known presence or absence of CHD as determined by a complete physical examination, including treadmill, resting ECG, and risk factor information. The validating sample consisted of 111 subjects drawn by a stratified-random procedure from 5000 available case histories. The CHD index was found to be significantly more valid as a sole indicator of CHD than the LCG without the use of the index. The index consistently produced higher validity coefficients in identifying CHD than did treadmill testing, resting ECG, or risk factor analysis.

Aerospace Medicine↗

A health study of employees exposed to vinylidene chloride.

Previous studies have reported on employee populations exposed coincidentally to vinylidene chloride in copolymer processes using vinyl chloride. The current study examines the mortality and health examination findings of 138 employees exposed to measured levels of vinylidene chloride where vinyl chloride was not used as a copolymer. There were no findings statistically related or individually attributable to vinylidene chloride exposure in this employee population. It is recommended that additional epidemiological studies be undertaken to develop data on chronic exposure to vinylidene chloride.

Alanine Transaminase↗

Mortality among individuals occupationally exposed to benzene.

The mortality experience of 594 individuals occupationally exposed to benzene was investigated using a retrospective cohort design. Three hundred thirty-five of the employees began working in benzene areas prior to 1950, which provided a sound data base from which to examine latency. Data derived from work histories and industrial hygiene records permitted estimation of exposure intensities and cumulative dosages for each employee. No mortalities directly attributable to benzene exposure were observed. Several cases of leukemia and other blood disorders were noted and discussed.

Anemia↗