Biomedical subjects
J C Steinmetz
Publications and source records attributed to J C Steinmetz.
Inoculating blood cultures: changing needles is useful.
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Simultaneous occurrence of congenital partial pericardial defect and posterolateral diaphragmatic hernia.
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Malignant chondroid syringoma with widespread metastasis.
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Neonatal hypertension and cardiomegaly associated with a congenital neuroblastoma.
A neonate who died 12 days after birth from complications related to a congenital neuroblastoma is described. Hypertension and congestive heart failure occurred soon after birth. Hospital course was marked by a consumptive coagulopathy and the development of acute renal and hepatic failure. At autopsy the heart was hypertrophied but normally formed. Although there was elevated urinary excretion of vanilmandelic acid and homovanillic acid, levels of epinephrine, norepinephrine, metanephrine, and normetanephrine were not documented. This case shows that a congenital neuroblastoma may be associated with hypertension and cardiomegaly in the neonatal period.
Hypersensitivity vasculitis associated with 2-deoxycoformycin and allopurinol therapy.
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Tissue levels of ibuprofen after fatal overdosage of ibuprofen and acetaminophen.
Ibuprofen is a non-steroidal anti-inflammatory agent which is relatively safe and effective for the treatment of inflammatory disorders, but there are several reports of acute poisoning due to ibuprofen overdosage. Although the majority of ibuprofen overdosages are not very serious, acute renal failure, hepatic failure, and hypotension and coma have been described. We report here the case of a 48-year-old male who committed suicide by ingesting overdosages of both ibuprofen and acetaminophen. The case is unique because of the role ibuprofen played in his death, and because we were able to measure levels of ibuprofen in tissues obtained from post mortem examination. Tissue levels of ibuprofen have not previously been reported in humans.
Changes of cellular markers during differentiation of HL-60 promyelocytes to macrophages as induced by T lymphocyte conditioned medium.
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Jaffe-Campanacci syndrome.
The case of a 15-year-old white boy with a clinical diagnosis of von Recklinghausen neurofibromatosis and a history of multiple fractures of long bones is presented. Radiographic studies and tissue biopsy revealed the presence of multiple nonossifying fibromas of bone. Review of the clinical features and correlation with the pathologic data support a diagnosis of Jaffe-Campanacci syndrome, a malformation syndrome different from but possibly related to von Recklinghausen neurofibromatosis.