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Biomedical subjects

J C Schoolar

Publications and source records attributed to J C Schoolar.

At least 37 records · Page 2Linked to original sources
PubMed1977

A family therapy outcome study in an inpatient setting.

A small sample of adolescents hospitalized in a public mental health facility received family therapy while a control group received individual therapy. Follow-up at three months indicated that those treated in family therapy returned to functioning more rapidly and were rehospitalized less frequently than adolescent patients in individual therapy. Directions for further study are suggested

Adolescent↗
PubMed1975

The effects of methadone on maternal-fetal interactions in the rat.

Female Sprague-Dawley rats received methadone (25 mg/kg/day) by gavage throughout gestation. Water-gavaged rats served as controls. Fetuses were delivered by cesarean section when parturition was imminent. Our results indicate that methadone may interfere with fetal development and maternal-fetal interactions to some degree. The observed alterations were as follows: fetal growth retardation, an interference with the triggering of parturition once normal delivery size is attained and possible positional malformations.

Abnormalities, Drug-Induced↗
PubMed1969

LSD: autoradiographic study on the placental transfer and tissue distribution in mice.

(14)C-lysergic acid diethylamide administered intravenously passed in a few minutes from the blood into the tissues. In addition to the brain, the adrenals, hypophysis, kidneys, liver, and lungs showed the highest uptake, much higher than the blood concentration. Excretion into the bile started immediately; this was the most inmportant elimination route. In the early stage of pregnancy, 2.5 percent (and in the late stage, 0.5 percent) of the radioactive dose passed the placental barrier into the fetus in 5 minutes. Over 70 percent of this fetal radioactivity was unchanged (15)C-lysergic acid diethylamide.

Animals↗