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J C Sabatier

Publications and source records attributed to J C Sabatier.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Progression and severity of arterial hypertension in aged subjects (12 cases].

We analyzed retrospectively 12 patients, aged from 63 to 73 years, with renovascular hypertension due to unilateral or bilateral atheromatous lesions (4 out of 12). Malignant or accelerated hypertension with multiple visceral involvement was frequent (8 out of 12). The proximal lesions (stenosis) of the renal arteries were rapidly progressive, leading to complete thrombosis in 8 cases. Five patients received medical treatment only, but 2 worsened their GFR and 2 had a poor blood pressure control. Of the 5 patients who underwent renal surgery 2 had nephrectomy, 2 had an aorto-renal bypass and 1 a bypass plus nephrectomy; 2 of them recovered a normal GFR, but 2 died in the post-operative period. Three patients had selective embolization of a renal artery, but only one was definitely improved. So far, the treatment of such cases still is very difficult.

Aged↗
PubMed1980

Primary retroperitoneal teratoma in adults: presentation of two cases and review of the literature.

Retroperitoneal teratomas are rare in adults; they are malignant in 25.8% of cases. The authors report two benign cases in which radiologic examination was essential in establishing the diagnosis. Irregular calcifications, which are visible in 61.5% of reported cases, cannot be considered a sign of benignity, since 12.5% of calcified tumors were malignant. Because of the indeterminate course of the disease, surgical removal is indispensable.

Adult↗
PubMed1980

Human glomerulonephritis and persistent non-polio enterovirus infection.

In a prospective work, we have studied the non-polio enterovirus (NPEV) excretion in spot urine and stools by four appropriate cell cultures, in four different groups: 20 exposed controls (GI), 88 patients with renal biopsy 'proven GN' (GII), 38 cases with 'proven nonGN' (GIII), and 9 with 'probable nonGN' (GIV). The positive excretion in stools and/or urine is respectively 0 and 5% in Group I, 14 and 33% in Group II, 6 and 19% in Group III, and 13 and 22% in Group IV. Viruria, the consequence of a viraemia, is therefore associated with 'proven GN' (p less than 0.05). In the majority of patients with positive NPEV excretion, we have made an additional but similar study, 3-12 months later. Persistent excretion was confirmed in 22/30 cases in Group II (73%) versus 0/8 in Group III-IV (p less than 0.001). These data concerned patients with membranoproliferative GN [5], membranous GN [6], mesangial IgA GN [6], endocapillary GN [2] or minimal lesions [3]. Thus we have demonstrated a significant relation between persistent NPEV urine/stools excretion and the occurrence of active GN in humans. Such persistent viral infections may represent the cause of some GN, probably mediated by an immune complex mechanism with viral antigens.

Enterovirus↗
PubMed1980

[Ultrasonography in the diagnosis of adrenal tumors (author's transl)].

A prospective study was conducted to assess the value of ultrasonography in the diagnosis of adrenal tumors. A limited number of cases (29 patients) was studied, to reduce the possible effects of human and technological progress. Ultrasonography can detect most adrenal tumors larger than 25 mm in diameter, more easily on the right than on the left. The solid or fluid nature of the tumor can be distinguished, but the benign or malignant etiology of the mass can only be determined when there is local and regional spread. Ultrasonography is particularly useful when a suspicious adrenal mass is seen on nephro-urotomography. The indications for ultrasonography have to be reconsidered, however, as a function of the results obtained with computed tomography.

Adenoma↗
PubMed1980

[Treatment of renal artery stenosis by percutaneous transluminal angioplasty (PTA) (author's transl)].

The preliminary results of treatment of the stenosis of renal artery by the transluminal percutaneous angioplasty (PTA) were presented. 6 patients were treated by the Gruntzig technique, 4 of the 5 patients probably having renovascular hypertension were returned to normal tension 2 to 5 months after treatment. The 6th patient had hypertension with severe renal insufficiency. The PTA was performed for the purpose of the inhibition of progressing renal insufficiency. This patient was stabilized. This preliminary experience show great interest of this technique.

Adult↗
PubMed1979

Normal variants of the sella turcica.

Complete study of the sella turcica requires multidirectional tomography. The authors have studied 200 radiographs of normal adults and noted the percentage of variants of each anatomical feature on both standard radiographs and tomograms. The greatest drawback of the standard radiograph is the difficulty in objectively evaluating the effect of pneumatization and/or a septum of the sphenoid sinus on the sellar floor. In this series the floor was concave in 58% of patients, flat in 32.5%, and convex in 9.5%. Lesions which simulate erosion of the posteromedial part of the lamina dura correspond to thinning of the central portion of the base of the dorsum sellae.

Adult↗
PubMed1979

Mesangial IgA glomerulonephritis in HLA-identical brothers.

Two HLA identical brothers with mesangial IgA glomerulonephritis are reported. Patient 1 developed gross hematuria at age 12 and required chronic hemodialysis at age 20. Patient 2 presented at age 21 with gross hematuria and normal renal function, the follow up period is only 9 months. Neither of these patients had nerve deafness, ocular defects or complement abnormalities. The family history did not support a diagnosis of classical hereditary nephritis, but a genetic linkage is strongly suggested by the identical HLA phenotypes of these brothers (A10 - A32 - B13 - B35). The B35 antigen has previously been suspected to be linked to this disease. These observations strongly support the hypothesis of an aberrant, genetically controlled, immune response, in patients with mesangial IgA glomerulonephritis.

Adolescent↗
PubMed1979

HLA Bw35 antigen and mesangial IgA glomerulo-nephritis: a poor prognosis marker?

Familial cases of mesangial IgA glomerulonephritis (MGN) have raised the possibility of a genetic control in this disease. In 50 patients with MGN, diagnosed on renal biopsy, and in 105 controls, we have compared the distribution of HLA antigens (A and B loci). We found a significant increase in the frequency of HLA Bw35 antigen in the patient group compared with controls (36% versus 13%: p less than 0.02). There was no significant difference between the Bw35 positive and negative MGN subgroups, in clinical, serological, and pathological data. Both subgroups had elevated mean serum IgA levels (154% of normal), and also mean serum IgM levels (146%). However, the follow-up data exhibited a significantly worse prognosis (p less than 0.01) in the Bw35 positive subgroup: 9 out of 18 patients versus 4 out of 32 progressed to chronic renal failure (serum creatinine greater than 1.5 mg/dl). We have established a genetic linkage between the HLA complex and the occurrence of MGN. The Bw35 antigen may serve as a marker (risk of disease = 4), in particular for poor prognosis cases.

Adult↗
PubMed1978

[Arterial hypertension and horseshoe kidney during Von Recklinghausen's disease. Angiographic study and review of the literature (author's transl)].

Angiographic studies in a young girl aged 16 years who developed arterial hypertension during the course of Von Recklinghausen's disease, demonstrated the presence of an obliterated renal artery in a horseshoe kidney. The distal arterial segment was revascularized by two homolateral ureteral arteries. A full review of the literature revealed 30 cases of renal artery lesions for which angiography had been carried out in young people with neurofibromatosis. This demonstrates the low incidence of obliterative lesions (4 cases throughout the world) which are always associated with collateral vascularization. It was not possible to apply the usual surgical treatment in our case because of the associated horseshoe kidney.

Adolescent↗
PubMed1978

[Congenital malformations of the inferior vena cava. Embryological, anatomical and radiological study (author's transl)].

Congenital malformations of the inferior vena cava are characterized by their diversity which is related to the complexity of the embryological development of this vessel. The authors review the embryogenesis and origin of the different segments of the inferior vena cava and describe the various types of malformation, including the causative embryological abnormality, ther frequency, possible clinical repercussions, and radiological aspects. Phlebocavography is essential for the identification of the various types of abnormality. Five different types of malformation are reported. Three of these are relatively rare (left inferior vena vaca, congenital membrane of the inferior vena cava, absence of the hepatic segment with continuation of the isolated azygos segment).

Adult↗
PubMed1978

[Inferior mesenteric arteriovenous fistula of congenital origin. A report on one case and review of the published literature (author's transl)].

A fourth case of inferior mesenteric arteriovenous fistula of congenital origin is described by the authors, who also review the general characteristics of mesenteric (or portal) arteriovenous fistulae. Early clinical signs are hemorrhage from the digestive tract and chronic anemia. Endoscopy and barium X-rays are normal, and angiography is the only means of diagnosis. Surgical treatment is essential because of the risk of hemorrhages and portal hypertension.

Adult↗