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Biomedical subjects

J C Rowlingson

Publications and source records attributed to J C Rowlingson.

At least 19 recordsLinked to original sources

Epidural steroids.

Although possessing a long history of use, the therapeutic use of epidural steroid injections still needs substantiation. Refinements in our understanding of the pathophysiology of radicular pain and in the techniques used to deliver depo-steroids to the target tissue will lead to improved clinical outcomes and fewer technique and drug-related side effects. Administration of epidural steroids at lumbar spine sites is more common than at cervical spine levels, although the same pain management concepts are applicable. Comparative studies are necessary to clearly define the advantages and disadvantages of the use of fluoroscopy and the transforaminal technique.

Animals↗

Organization of a multidisciplinary pain center.

Chronic pain is a complex, multifaceted experience that leads not only to disability and dysfunction but also to suffering and unrealized human potential. To be effective, a pain management center must be multidisciplinary in concept as well as practice. It must employ practitioners whose assessments are not restricted to specialty interests. They must communicate effectively with other specialists and cooperate to design and implement the best treatment program for each patient. The ultimate goal is rehabilitation of the patient to a more functional life despite residual pain. This may involve breaking the doctor-shopping cycle for those patients seeking cure, detoxification to more appropriate medications, addressing personal and family conflicts through counseling, assisting the patient in resolving socioeconomic problems, and, ultimately, teaching the patient to function more effectively within the bounds of any physical limitations.

Ambulatory Care Facilities↗

Reflex sympathetic dystrophy in children: treatment with transcutaneous electric nerve stimulation.

During the past 6 years, ten children with reflex sympathetic dystrophy were treated. Pain in an extremity was the initial complaint in all patients. The pain was unilateral in 90% of the patients; upper and lower extremities were affected with equal frequency. Tenderness to palpation, extreme hyperesthesia, and dysesthesia were other dominant features. All patients had some evidence of autonomic nervous system dysfunction in the affected extremity (swelling, color change, decreased temperature, and/or hyperhidrosis). The median duration of symptoms prior to referral and diagnosis was 5 months. All children were treated as outpatients with a transcutaneous electric nerve stimulator and home-based physical therapy. With this regimen, seven patients had complete remission within 2 months. Two other patients improved with transcutaneous electric nerve stimulation therapy, and one patient had no response to transcutaneous electric nerve stimulation. Reflex sympathetic dystrophy is frequently underdiagnosed in children. Increased awareness of this syndrome is important because accurate diagnosis is crucial and transcutaneous electric nerve stimulation offers a safe, simple, and effective outpatient therapy for reflex sympathetic dystrophy in children.

Adolescent↗

The Balans chair and its semi-kneeling position: an ergonomic comparison with the conventional sitting position.

Recently, the Balans chair has been introduced with claims that, because of its semi-kneeling position, individuals will experience decreased low-back pain (LBP) as well as improvement in circulation. This study investigated the validity of these claims. Twenty healthy subjects were randomly assigned to one of two groups. Group 1 subjects sat in the Balans chair for a 30-minute study period and then sat in a conventional office chair for an additional 30-minute period. Group 2 subjects were studied in the reverse seating order. Parameters studied were cervical and lumbar paraspinous surface EMG, and pedal cutaneous blood flow measured by laser-Doppler flowimetry. In addition, a questionnaire comparing the comfort of the two chairs was completed at the end of the study session. Comfort ratings showed an overall preference for the conventional chair. Increased cervical (P = .004) and lumbar muscle EMG measurements were noted after sitting in the Balans chair. Pedal cutaneous blood flow was increased by 15% in the Balans chair (P = .001). The data do not support the manufacturer's claim that the Balans chair is likely to decrease complaints of LBP.

Adult↗

Epidural analgesic techniques in the management of cervical pain.

The injection of depot steroids into the cervical epidural space can maximize the conservative management of patients with cervical radiculopathy. We retrospectively studied 25 patients with cervical radiculopathy who received a total of 45 epidural injections of steroids. Sixty-four percent of the patients had a good or excellent response to cervical epidural steroid injection, whereas other conservative treatment modalities had not helped them. The patient's history and a description of the pain and the corresponding neurological abnormalities present were of value in the selection of patients who were most likely to respond favorably to epidural steroids, whereas laboratory studies were not as useful. Anesthesiologists, many already familiar with the use of epidural steroid injection in the treatment of low back pain, should add to their armamentarium the use of such techniques in the management of patients with acute and chronic cervical radiculopathy.

Adult↗

Frostbite.

Explore the source record for details and available documents.

Child↗

Anesthetic potency of dezocine and its interaction with morphine in rats.

A new partial agonist-antagonist analgesic drug, dezocine, was evaluated in rats for its anesthetic potency using a MAC-reduction model. Respiratory effects as shown by changes in PaCO2 were also analyzed. A reduction of approximately 50% in cyclopropane MAC was found with doses of 6 mg/kg or more. This is the largest reduction for any drug of this class. PaCO2 levels increased up to 52 mm Hg with doses of dezocine up to 2 mg/kg. No evidence of reversal of respiratory depression or of further respiratory depression was found with increasing dosages. Combining dezocine with morphine resulted in a further reduction in cyclopropane MAC without a significant change in PaCO2. This suggests that dezocine acts primarily on the same receptor (mu) as morphine and that this receptor activity is further modulated by effects of dezocine on a second opioid receptor.

Anesthetics↗

Treatment of bladder pain with transsacral nerve block.

Fifteen patients with bladder spasticity and pain of three different etiologies were referred to the pain clinic by urologic specialists. These patients were refractory to all prior methods of treatment, excluding major surgical procedures. In a prospective study started in 1976, these patients were treated with transsacral nerve blocks using 0.25% bupivacaine and, in most cases, subsequent 6% aqueous phenol at the right S-3 ventral foramen. If indicated, transsacral nerve blocks were performed at other levels, as described in the text. Of the patients studied 53% have had significant or complete relief of pain for an average of 26.5 months. The associated morbidity was negligible and there was no mortality. This is in contrast to the morbidity and mortality associated with some major surgical "curative" procedures. The technique is proposed as a successful and economical approach to treatment that can be managed on an outpatient basis.

Bupivacaine↗