Search PubMed⌕ Search

Biomedical subjects

J C Masdeu

Publications and source records attributed to J C Masdeu.

84 records · Page 5Linked to original sources
PubMed1981

Postischemic hypervascularity of infancy: a stage in the evolution of ischemic brain damage with characteristic CT scan.

One to 2 weeks after severe brain ischemia, four infants developed an unusual vascular lesion with a characteristic appearance on computed tomography that has not been reported previously. Restricted areas (most frequently the basal ganglia and thalamus) displayed increased attenuation, which enhanced further upon infusion of contrast medium. Autopsy of one infant revealed that the CT abnormality corresponded to an extremely dense neovascular network which had almost completely replaced the parenchyma in that region. We postulate that this pathological change is a stage in the organization of ischemic brain damage reflecting the infant's vascular plasticity. Thus, hypoxia induces marked capillary proliferation in regions of normally high metabolism and capillary density. The CT pattern may prove useful in predicting the location and extent of sequelae to perinatal asphyxia.

Asphyxia Neonatorum↗
PubMed1980

Delayed radiation necrosis of the brain contralateral to original tumor.

In a 23-year-old man, radiation necrosis developed in the left hemisphere after radiation of a right-sided intracranial tumor. Since normal tissue had to be resected around the tumor, the contralateral temporal lobe received the highest cumulative radiation dose for brain tissue. This report underscores the need for careful reconstruction of the radiation isodose distribution when considering the differential diagnosis of postradiation brain lesions.

Adult↗
PubMed1979

Spinal subarachnoid hematomas: clue to a source of bleeding in traumatic lumbar puncture.

Although damage to the veins of Batson's epidural plexus is usually considered the origin of bleeding in traumatic lumbar puncture, a lesion of these veins would not explain the cases in which postmortem examination shows blood confined to the subdural and subarachnoid spaces. In two patients who had lumbar punctures a few days before death, there was subarachnoid hematoma of the cauda equina at autopsy. In one of these cases, the radicular vessels were shown to be the source of bleeding. Spinal subarachnoid and subdural hemorrhages after lumbar puncture may be due to laceration of radicular vessels by the spinal needle.

Adult↗
PubMed1977

Evaluation of recent cerebral infarction by computerized tomography.

Twenty patients with cerebral infarction were observed with serial computerized tomographic (CT) scans. Seventy percent of those infarctions showed a mass effect that had disappeared in all patients by the eighth week after the ictus. In 63%, there was enhancement after contrast infusion, with a definite temporal relationship to the day of onset of the neurological deficit. Twenty percent of the patients initially had normal CT scans that became abnormal weeks after the stroke. Radionuclide scans were positive in the patients who showed contrast enhancement, and the area of abnormal uptake correlated well with the area of enhancement. The timing of the performance of the CT scan in relation to the onset of neurological deficit is an important factor to consider when evaluating the stroke syndrome with CT.

Humans↗
PubMedDate not supplied

Primary reading epilepsy.

In six cases of reflex epilepsy, the seizures were triggered by reading or elaborating a verbal utterance, and were accompanied on EEG by focal or generalized epileptiform activity. The seizures were controlled with clonazepam in four cases and by sodium valproate in two cases. We speculate that the disturbance has a cortical origin and is triggered by neural processes involved in the elaboration of language.

Adult↗
PubMedDate not supplied

Infarct versus neoplasm on CT: four helpful signs.

In a search for distinguishing features, the computed tomographic (CT) findings in 35 patients with recent cerebral infarction and 65 patients with cerebral neoplasms were compared. Gray-matter enhancement and sparing of the thalamus characterized infarcts; white-matter edema and ring enhancement located in the white matter favored the diagnosis of neoplasm.

Brain Edema↗