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Biomedical subjects

J C Martin

Publications and source records attributed to J C Martin.

At least 325 records · Page 18Linked to original sources
PubMedDate not supplied

Neonatal neurobehavioral outcome following prenatal exposure to cocaine.

This substudy of a longitudinal prospective study was designed to assess neurodevelopmental and neurobehavioral performance in newborn infants who were maternally exposed to cocaine and other drugs of abuse or the other drugs without cocaine. Sample selection procedures were designed to permit statistical control for marijuana, alcohol, and tobacco. Cocaine was assessed with both self-report and radioimmunoassay of hair. One hundred ninety-one newborns with a mean age of 43 h were assessed for 35 to 40 min on tests of reflexes, activity level, head-turning preference, tremors, nonnutritive sucking, habituation, and state. The testers were blinded to the baby's drug exposure. Cocaine-exposed newborns were developmentally at risk on the tests administered compared to infants exposed to the other three drugs alone or in some combination. A dose-response effect was found: higher amounts of cocaine were associated with higher neurobehavioral risk scores.

Adolescent↗
PubMedDate not supplied

[Experimental granulomas].

The various techniques used for obtaining granulomatous lesions are reviewed, account being taken of the type of animal, the organ, the inducing agent and its mode of administration. The different aspects of the granulomatous lesions are then described with respect to the cell population examined and to the dynamic of the macrophagic behaviour within the lesions, the dynamics making it possible to make a classification according to the rate of renewal of the cell population concerned. Some particular cases are examined, in particular with regard to the interactions of the granuloma with other pathological processes such as bacterial infection or immunitary reactions.

Animals↗