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Biomedical subjects

J C Mall

Publications and source records attributed to J C Mall.

34 records · Page 2Linked to original sources

A unified radiological approach to the detection of skeletal metastases.

Radiographic bone surveys and radionuclide images, the principal methods of detection of skeletal metastases, have traditionally been treated as separate entities. Since their interpretation is reltaed, we attempted to determine the practicability of a unified radiological approach which employs both methods. All consultation requests for "skeletal surveys" or bone scans were reviewed, and an appropriate examination was "tailored" for each patient. During the inital four-month period, 141 patients were examined. Comparison of the final "tailored" examination with the original consultation request indicated that, without radiological guidance, excessive (18%), and inappropriate or inadequate (27%) examinations were ordered in many cases. The unified approach has proven to be feasible and desirable, resulting in a significant reduction of inappropriate examinations.

Bone Neoplasms↗

Efficacy of emergency radionuclide perfusion lung studies.

Over a one-year period, 206 patients with suspected pulmonary embolism received gamma camera perfusion lung images on an emergency 24 hr. basis. Clinical diagnosis listed pulmonary embolism in 37 of 39 patients whose images showed a high probability of it, in 28 of 69 whose images were abnormal but rated uncertain probability, and 5 of 98 with normal images. Retrospective clinical evaluation indicated 89 of the emergency images to be considered important, 95 contributory, and 22 not helpful in clinical management. As a result of the images, 80 patients were placed on heparin therapy of 198 considered for it, and 22 of 29 patients referred for hospital admission were placed on an outpatient basis. Delay in obtaining lung images creates the possibility of diagnostic uncertainty in interpreting the image.

Adolescent↗

Matrix calculi.

Matrix calculi are an uncommon form of urinary tract concretion. They must be considered in the differential diagnosis of a radiolucent mass within the renal collecting system or ureter. The clinical and radiographic features of three cases are presented and the literature of matrix calculi is reviewed.

Bacteriuria↗

Optical versus radiographic magnification for fine-detail skeletal radiography.

Fine-detail radiographic techniques for peripheral skeletal imaging have gained wide clinical acceptance. In this study, the imaging properties and clinical applications of the optical magnification technique, which employs fine-grain industrial film and a large focal spot, are compared quantitatively and qualitatively with those of three slow screen-film techniques, namely, contact exposure with a large focal spot, 2 times radiographic magnification with a 0.3 mm focal spot, and 4 times radiographic magnification with a 50 mu focal spot. The modulation transfer functions (MTF's) of the recording systems and focal spots are obtained and film sensitometry performed. Clinical comparisons are made for patients with metabolic, arthritic, and neoplastic skeletal disorders. The results illustrate the superiority of the optical magnification technique over contact or 2 times magnification techniques using slow screen-film systems. If a microfocus tube is used, however, direct radiographic magnification may provide images comparable in resolution, noise and contrast to those made with the optical magnification technique, and at lower radiation exposure to the patient.

Arthritis, Rheumatoid↗

Comparison of non-screen techniques (medical vs. industrial film) for fine-detail skeletal radiography.

High resolution radiographic techniques for imaging the peripheral skeleton (hand and foot) have gained wide clinical acceptance. The two procedures receiving widest attention are non-screen techniques: one uses medical film (Kodak RP); and the other uses industrial film (Kodak Type M) combined with optical magnification. The imaging properties and clinical applications of these two techniques were examined. The modulation transfer functions (MTF's) of the recording systems, Wiener spectrum analyses of noise, and film sensitometry were obtained. Clinical comparisons were made from 200 consecutive patients radiographed with both techniques and the relative merits in metabolic, arthritic and traumatic afflictions were assessed. The results demonstrate the superiority of the industrial film compared to medical film technique in all parameters of image quality. However, the inconveniences of special processing and viewing necessitated by this technique, as well as the increased radiation exposure, limit its clinical application to small, selection groups of patients as determined from the clinical comparative study.

Arthritis↗

Skeletal demineralization and growth retardation in inflammatory bowel disease.

Skeletal growth and mineralization in 54 adolescent and adult patients with inflammatory bowel disease have been analyzed comprehensively. Quantitative and qualitative radiologic techniques consisted of conventional roentgenography, photon absorptiometry, and radiographic morphometry. The data are correlated with the type, duration, and severity of disease, and with several modes of therapy. The results indicate the osteopenia and retardation of growth are common in patients with inflammatory bowel disease, particularly in adolescents, in whom the effects of corticosteroids on the skeleton are most deleterious.

Adolescent↗