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Biomedical subjects

J C Gupta

Publications and source records attributed to J C Gupta.

At least 19 recordsLinked to original sources
PubMed1980

Amyloidosis in leprosy.

Fourteen hundred and forty five biopsied tissues of various organs including liver, skeletal muscle, kidney, lymphnode, larynx and skin from 1222 patients of leprosy obtained during the last 10 years have been examined histopathologically to study various types of pathological lesions. These patients ranged in age from 7 years to 72 years and the duration of illness varied from less than one year to twenty years. Although the presence of lepromatous granuloma, AFB in varying proportions, and some nonspecific lesions have been observed in them, but amyloidosis was not detected in any of them. This finding is discussed in view of the observations of other authors of different parts of the world in this connection. Consumption of mainly vegetarian diet in our population and that of meat in Western population has been suggested to be the probable cause of the difference of amyloidosis observed in the two groups of people.

Adolescent↗
PubMed1980

A clinico-pathological study of laryngeal lesions in 30 cases of leprosy.

The histological findings in laryngeal biopsies and local clinical findings in thirty cases of leprosy have been reported in detail. It is emphasised that in areas where there is significant incidence of leprosy, laryngeal involvement may be expected even in the absence of local clinical manifestations and be got confirmed by histological examination and demonstration of acid-fast bacilli. Further, histological appearance may not be very characteristic at the outset. The observations made by previous authors have been reviewed and discussed.

Adult↗
PubMed1978

A histopathological study of lymphnodes in 43 cases of leprosy.

Eighty cases of leprosy including 60 cases of lepromatous type and 20 cases of tuberculoid type, during the period of 1974-75, have been examined for evidence of lymphnode enlargement. Of the 52 cases of enlarged lymphnodes, lymphnode biopsy was done in 43 cases including 38 cases of lepromatous type and 5 cases of tuberculoid type. The lymphnodes have been studied for evidence of any pathological changes and presence of acid-fast bacilli. In cases of lepromatous leprosy, lepromas and acid-fast facilli were seen in 92.2 per cent of the cases and patchy fibrosis was noted in 23.6 per cent of the cases. No amyloid could be demonstrated. In cases of tuberculoid leprosy, only non-specific reticular hyperplasia was noted. No specific granuloma or acid-fast bacilli could be demonstrated. The findings have been described in detail and discussed in the light of previous published data.

Adolescent↗