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Biomedical subjects

J C Daubert

Publications and source records attributed to J C Daubert.

At least 109 records · Page 6Linked to original sources
PubMed1978

[Myocardiopathies during pregnancy. Possible role of beta-mimetics].

The authors report two cases of severe non-obstructive cardiomyopathy presenting at the end of pregnancy in young women treated for long periods and at high dosage with beta 2-adrenoceptor stimulants, prescribed for threatened abortion or premature labour. The circumstances of the presentation, the clinical prescribed for threatened abortion or premature labour. The circumstances of the presentation, the clinical picture and the course towards complete recovery suggest that this might be a pathological process different from "cardiomyopathy of pregnancy" and be an "adrenergic myocarditis" induced or made worse by these drugs. The authors deduce some simple preventive measures.

Adrenergic beta-Agonists↗
PubMed1978

[The cardiomyopathy of idiopathic hemochromatosis].

A retrospective study of the case histories of 216 patients with idiopathic haemochromatosis has highlighted the frequency of cardiac involvement in this condition (53%). Two forms can be distinguished: a latent one (65%), in which the changes are predominantly electrocardiographic, and a clinical form (35%) with the features of congestive cardiomyopathy, notable for the rapidity of onset after right heart failure, the degree of cardiomegaly, the constant finding of abnormalities of ventricular repolarisation, the relative frequency of latent disorders of supra-His atrio-ventricular conduction, and the finding of elongation of the isovolumic contraction time on the phonomechanocardiogram. A haemodynamic profile is the same as for non-obstructive hypotonic cardiomyopathies, and is usually associated with a slow rise in left ventricular pressure. The cardiomyopathy, which is the most frequent cause of death, determines the prognosis in this condition. It may be found in association with diabetes and gonad failure. The finding of cardiomyopathy indicates basic treatment by veresection, which may be the only means of establishing a favourable outcome.

Adult↗
PubMed1977

[Infarction of the right ventricle. 1. Hemodynamic diagnosis; pathologic correlations].

70 patients with acute myocardial infarction were submitted to a full haemodynamic assessment at the onset of the condition. In 28 of them there was a disproportionate rise in the right ventricular end-diastolic pressure which could not be explained on the basis of a primary rise in left ventricular filling pressures; these were divisable into two subgroups: -- 19 infarcts without septal rupture, almost all with an inferiorly or posteriorly placed lesion (17); in these cases, an analysis of the curves shows, among other features, a syndrome of adiastole whose three forms (minor, moderate or severe) correlate well with the clinical features. Six cases died, and in four of those it was possible to study the correlation with the post-mortem findings: there were major lesions of the free wall of the right ventricle in 3 cases, but constrictive pericardial changes, the main differential diagnosis of right ventricular infarction, in the fourth. -- 9 cases of necrosis of the septum with rupture, of which only 3 had a syndrome of adiastole; three of these necroses were posterior, and post-mortem examination in two of them confirmed that there were indeed major lesions in the posterior wall of the right ventricle. It therefore seems that the diagnosis of infarction of the right ventricle is a haemodynamic one, and rests especially on the discovery of a syndrome of adiastole. Findings such as these are confined almost exclusively to posteriorly placed infarctions.

Cardiac Output↗
PubMed1977

[Infarction of the right ventricle. 2. Prognostic and therapeutic aspects].

Infarctions of the right ventricle have a reputation for being innocuous which appears to be unjustified; in a group of 21 patients in whom the diagnosis has been based on the haemodynamic principles put forward in the previous paper, we have had 7 deaths. The prognosis appears to be determined by two types of complication: ruptures of the posterior septum (4 cases), which are very distinctive in their clinical and topographical picture; and haemodynamic complications (10 cases of decompensation) which are related fairly rarely with the lesion of the right ventricle (2 cases), but more often with an associated complication, especially hypovolaemia, in which state the involvement of the right ventricle seems to play a particularly major role in increasing the slowing of the circulation. The proposed treatment plan is aimed at the permanent establishment of an effective circulating volume in the uncomplicated cases; in cases with complications, the aims are twofold--filling of the vascular bed and vasodilators, either separately or simultaneously.

Aged↗
PubMed1977

[Familial long QT-syncope syndrome. 2 cases of Romano-Ward syndrome].

Two families with the Romano-Ward syndrome were studied; in family A there were 19 members from three generations, 11 of whom had the abnormality of a long QT interval, 2 of whom had fainting attacks, and 2 of whom died suddenly. In family B, comprising 5 members of two generations, 3 had the anomaly, one of these having fainting attacks, and also having an atrio-ventricular block. The bicycle ergometer test has an important part to play in decisions about treatment of the asymptomatic forms of the condition.

Adolescent↗
PubMed1976

[Coronary insufficiency in pheochromocytoma].

The authors report the case of a 42 year old female with a phaeochromocytoma who, in the course of a hypertensive episode, had ECG changes typical of a myocardial infarction. These changes regressed within a few days. A normal coronary arteriogram confirmed the purely functional nature of this episode of acute myocardial ischaemia. In addition to the case report, the authors discuss the physio-pathological and electrocardiographic features of the coronary insufficiency of phaeochromocytoma, and also the problem of the rapide regression of the changes of infarction on the ECG.

Adrenal Gland Neoplasms↗
PubMed1976

[Mitral stenosis and partial abnormal pulmonary venous return. 3 case reports].

The association of mitral stenosis with an abnormal pulmonary venous return in the absence of an atrial septal defect, is a rare occurrence, and three cases are reported here. If this diagnosis is suggested by the chest Xray, it is confirmed by haemodynamic investigation, which defines the abnormal pulmonary drainage, guages the size of the left-right shunt, and demonstrates the degree of mitral steonsis. If the defect is poorly tolerated, surgical treatment is required.

Aged↗
PubMed1976

[Abnormal pulmonary venous return from the right lung into the inferior vena cava or scimitar syndrome. 2 cases: hemodynamic study and surgical correction].

Two cases of abnormal venous return from the right lung into the inferior vena cava, or the scimitar syndrome, have been studied. The essential features of this condition are given, emphasis being laid on the haemodynamic findings. Surgical correction of the abnormal pulmonary venous return seems to be a logical solution when the left-right shunt is of significant size.

Adult↗
PubMed1975

[Comparative study of metabolic criteria of acute myocardial ischemia in man].

The study of various myocardial metabolic substrates in basal conditions and in the course of an atrial pacing test in two groups, one control, and the other including angina pectoris in patients with sound coronary arteries, provides the confirmation that the only valid metabolic criterion for acute myocardial ischaemia in man is represented by the decreased extraction or production of lactates. The sugnificance and the specidicity of this parameter is discussed.

Acute Disease↗
PubMed1975

[Disputable thoracic pain with normal coronary arteries. Metabolic study].

The search for electrocardiographic, haemodynamic and above an metabolic criteria suggestive of "myocardial ischaemia" in the course of an atrial pacing test was found to be positive in three patients suffering from atypical thoracic pains, and in whom selective coronary arteriograms might be considered as normal. It appaear thus that the criterion of a normal coronary arteriography and a negative or unsignificant effort test is insufficient to discard the diagnosis of "myocardial ischaemia" when confronted with such pains habitually considered as anorganic. The accurate mechanism of these pains, probably identical to that or those of "angina with normal coronary arteriography" remains undecided.

Adult↗
PubMedDate not supplied

[Value of hemodynamic evaluation in infarction of the right ventricle].

Right cardiac catheterisation was the first method of investigation proposed for the diagnosis of right ventricular dysfunction during the acute phase of biventricular myocardial infarction. With the development of non-invasive methods of investigation (radio-isotopes and particularly ultrasonography), the value of haemodynamic surveys has become open to question. This paper aims to demonstrate that this minimally traumatic investigation, which can be performed in any intensive care unit, is still useful: for the diagnosis of infarction of the right ventricle (RV), as, provided it is performed sufficiently early in the course of the disease and possibly associated with a filling test to increase the sensitivity, it provides very specific and very sensitive criteria: disproportionate elevation of the RV filling pressure, morphological syndrome of adiastole; for the diagnosis of associated mechanical complications: tricuspid incompetence, by analysis of the curve of the RA pressure; intraventricular shunt due to septal perforation or a right-to-left shunt during atrial relaxation through an intra-atrial communication or PFO, by means of staged oximetry; for the analysis of the distal effects of the RV dysfunction: RV filling pressure and cardiac output; and finally, by means of haemodynamic monitoring, for the orientation and monitoring of treatment in the severe forms responsible for a low output state.

Cardiac Catheterization↗
PubMedDate not supplied

[Exercise tests before and after aortocoronary bypass].

A stress test was performed before and after by-pass grafts in 83 patients. Post-operatively, the number of painful stress tests fell from 68 to 28. Whatever the initial clinical picture (stable angina, anterior or inferior infarct), the improvements is significantly better when all of the lesions have been by-passed. Furthermores, there was no significant change in the maximal performance, but the appearance of pain occurred at much higher values, reflecting the improvement in coronary perfusion and the displacement of the point of appearance of ischaemia.

Adult↗