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Biomedical subjects

J C Caporossi

Publications and source records attributed to J C Caporossi.

6 recordsLinked to original sources
PubMed1989

Mortality patterns among workers exposed to acrylamide.

A cohort of 8854 men, 2293 of whom were exposed to acrylamide, was examined from 1925 to 1983 for mortality. This cohort consisted of four plant populations in two countries: the United States and The Netherlands. No statistically significant excess of all-cause or cause-specific mortality was found among acrylamide workers. Analysis by acrylamide exposure levels showed no trend of increased risk of mortality from several cancer sites. These results do not support the hypothesis that acrylamide is a human carcinogen.

Acrylamide↗
PubMed1989

Mortality patterns among employees exposed to acrylonitrile.

A cohort of 2671 men, 1774 of whom were exposed to acrylonitrile, was observed from 1951 through 1983 for mortality. No statistically significant excess of all-cause or cause-specific mortality was observed. Analysis of exposure duration to acrylonitrile with respiratory cancer mortality showed no trend. Men exposed to high levels of acrylonitrile had respiratory cancer rates similar to men not exposed in the workplace and to the US general male population. These study results do not support the hypothesis that acrylonitrile is a human carcinogen.

Acrylonitrile↗
PubMed1989

Mortality patterns among men exposed to methyl methacrylate.

A cohort of 2,671 men, 1561 of whom were exposed to methyl methacrylate, was observed from 1951 to 1983 for mortality. This cohort consisted of men from two plants. This study utilizes detailed exposure estimates and smoking status to evaluate mortality patterns. We find no statistically significant excess all-cause or cause-specific mortality. Analysis of dose of methyl methacrylate with several cancer sites showed no trend. Men exposed to high levels of methyl methacrylate had cancer rates similar to those for men not exposed in the workplace, as well as for other men in the US population. An earlier epidemiology study reported a significant excess of colorectal cancer among persons exposed to several substances including methyl methacrylate. Our study results and results from animal studies do not support the hypothesis that methyl methacrylate is a human carcinogen.

Adult↗
PubMed1983

Computing partial-shift respirator use periods.

Occasionally, airborne contaminant concentrations cannot be reduced to desired levels, even after the installation of feasible engineering controls. The industrial hygienist may have to recommend full-shift or partial-shift use of appropriate respirators to reduce exposures. The method described allows the industrial hygienist to recommend the minimum period of time an exposed employee needs to use a respirator in order to reach the desired exposure level. The procedure is based on the calculation of Time-Weighted Averages, using the upper confidence levels of air sampling data, and the respirator protection factors.

Air Pollutants↗
PubMed1979

A validation procedure for air sampling-analysis systems.

Validation of solid sorbent air sampling-analytical systems used to evaluate employee exposures to substances in the work place air is a fundamental part of any industrial hygiene air sampling program. In April, 1977, the National Institute for Occupational Safety and Health (NIOSH) published "Documentation of the NIOSH Validation tests", as part of the Standards Completion Project. This paper presents an alternative validation procedure which is more easily understood, is more rigorous, and provides for greater accuracy and precision.

Air Pollutants↗