Biomedical subjects

J C Buell

Publications and source records attributed to J C Buell.

27 records · Page 2Linked to original sources

PubMed1982

Bio-behavioural perspectives on coronary heart disease, hypertension and sudden cardiac death.

A series of research developments is described which together consider the problem of the relationships between behavioural, physiological and pathophysiological processes. Arguments are advanced for the measurement of challenge-induced changes in haemodynamic responses for use in the understanding, prediction and control of coronary heart disease (CHD), hypertension and sudden cardiac death. A methodology is presented as a possible tool for accomplishing this latter goal and preliminary data are reported in support of the feasibility of these methods. Finally, basic pathophysiological mechanisms in cardiovascular disorders are examined in relation to potentially damaging haemodynamic activity.

Blood Pressure↗

PubMed1981

Challenge-induced cardiovascular response as a predictor of minor illnesses.

Male college students (n = 64) participated in a competitive "TV tennis game" while their heart rate and blood pressure were monitored. Subsequently, their health records were inspected to determine frequency of illnesses. Subjects who responded during the contest with extreme increases in heart rate and diastolic blood pressure were significantly more likely to have frequent minor illnesses than those responding with moderate or low increases.

Blood Pressure↗

PubMed1980

Psychosocial and behavioral influences in the pathogenesis of acquired cardiovascular disease.

When taken together, studies relating psychosocial and behavioral factors to cardiovascular disease phenomena provide justification for the conclusion that such factors are importantly involved. We would emphasize the need to study and evaluate the interaction of environmental and biological factors in both laboratory studies of pathogenesis as well as in clinical studies of management. Indeed, upon careful scrutiny, even the accepted "nonbehavioral" risk factors such as hypercholesterolemia, hypertension, cigarette smoking, obesity, and sedentary lifestyles are each composite manifestations rather than single pathogens whose identities are powerfully impregnanted and bolstered by varieties of behavioral and psychosocial underpinnings. In view of the awesome impact of contemporary cardiovascular disease, both in terms of its increasing socioeconomic importance and its biologic devastation, we can not long afford comprehensive public health programs without increased and improved attention to psychosocial and behavioral influences in the pathogenesis of acquired cardiovascular disease.

Animals↗

PubMed1980

Cardiovascular responses to emotional stress (quiz interview) in post-myocardial infarction patients and matched control subjects.

In this investigation, 30 male post-myocardial infarction patients and 30 male control subjects matched according to age and occupation were given a 12-minute tape-recorded stress quiz described by Schiffer et al. Cardiovascular responses (electrocardiogram, heart rate, systolic, blood pressure, and diastolic blood pressure) to emotional stimuli were monitored in a laboratory setting at rest before the quiz and at two-minute intervals during the quiz. Heart rate and blood pressure values were significantly higher during the quiz than at rest for both patient and control groups. There was a significantly higher response for diastolic pressure and a significantly lower response for heart rate in the patient group compared with the control group. In the analysis for occupational status in the entire population, systolic pressure was significantly higher for the executives than for non-executives. Subgroup analyses of patients with angina, hypertension and/or ECG changes (N = 12) revealed a significantly higher diastolic pressure response than found in either the patients without these symptoms (N = 18) or in the controls (N = 30). In comparison to exercise test results, the emotional stress test (quiz) elicited somewhat more PVC's but less ST segment depression. These results support previous reports suggesting that emotional stress testing may be a valid tool in the diagnosis of coronary heart disease and in determining the physiological mechanisms which underlie the association between emotional stress and coronary heart disease.

Adult↗

PubMed1979