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Biomedical subjects

J C Adkins

Publications and source records attributed to J C Adkins.

25 records · Page 2Linked to original sources
PubMed1981

Toxic megacolon developing in a patient with long-standing distal ulcerative colitis.

A young male with an eight-year history of stable distal ulcerative colitis acutely developed a toxic megacolon with mucosal involvement of the entire rectum and colon. This rare fulminant progression of previously stable disease underscores the lability of clinical severity of inflammatory bowel disease and the need to respond therapeutically to each recrudescence of symptoms on the basis of the severity of these symptoms and not the previously determined extent of colonic involvement.

Adult↗
PubMed1980

Ondine's curse and neurocristopathy.

A newborn with congenital neuroblastomas, Ondine's curse (central hypoventilation) and Hirschsprung's disease is presented. All lesions may be related embryologically and might fall under the general heading of neurocristopathy.

Abdominal Neoplasms↗
PubMed1977

The operative management of von Recklinghausen's neurofibromatosis in children, with special reference to lesions of the head and neck.

Eighty-five patients with von Recklinghausen's neurofibromatosis were seen at the Children's Hospital of Pittsburgh from 1952 through 1976. Nineteen of these patients had significant head or neck extracranial lesions. Based upon these and a personal series of seven other head and neck patients, we emphasize several critical points in the care of these patients: (1) large, painful, conspicuous, or strategically placed tumors should be removed: (2) early removal is easier and improves cosmetic results; (3) neck and chest tumors carry a high risk of subsequent rapid vertebral angulation with possible paralysis; (4) close observation allows timely application of appropriate surgical procedures.

Adolescent↗
PubMed1976

Imperforate anus.

Sucessful treatment of the child with imperforate anus yields an individual with satisfactory continence and a healthy urinary tract. These goals are achieved by accurate evaluation of the newborn, optimal technical results, and conscientious follow-up. The infant born with one of these malformations frequently has a serious associated anomaly which also requires early specific diagnosis and management. When the bowel has passed through the puborectalis in utero, the deformity can often be definitively treated in the neonate by dilations or anoplasty. However, if a urinary or high vaginal fistula is present, or if the anomaly is of the supralevator type, definitive surgery is best postponed some months and the neonate given a colostomy. We have found the sacroabdominoperitoneal approach to be the most satisfactory pullthrough procedure for the supralevator lesion. The children with high, supralevator anomalies have higher mortality rates and, in one out of four cases, have suboptimal fecal continence. They require the utmost in technical skill and continuing care if they are to lives free of social stigma. The mortality rate in all other types is low and the functional continence uniformly acceptable.

Abnormalities, Multiple↗