Biomedical subjects
J Bukowski
Publications and source records attributed to J Bukowski.
New delivery unit for National Women's Hospital.
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[Clinical trial of lithium salts in the states of chronic psychomotor agitation].
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[Carcinoembryonic antigen (CEA) in the serum of patients with cancer of the colon and rectum].
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[Preliminary results of the analysis of the carcinoembryonic antigen (CEA) level in the serum of patients with dysplasias and benign neoplasms of the breast].
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[Carcinoembryonic antigen (CEA) in breast cancer].
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[Neoplastic encephalopathy in the light of 2 observed cases].
The authors report two cases of neoplastic encephalopathy. In one patient with oviduct carcinoma it had the form of cerebellopathy. In the other case of renal carcinoma it appeared as encephalopathy with a nearly exclusive involvement of cerebral hemispheres. The reaction of microglia, lymphocytes and diffuse demyelination found in these cases are regarded by the authors as a result of autoimmunization in the course of malignant neoplasm. Attention is called to the importance of axial computer tomography in the intravital diagnosis of this encephalopathy.
[Percutaneous mediastinal aspiration biopsy].
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[Activation of the EEG records after alcohol drinking].
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[Case of spontaneous intracerebral hematoma with subsequent development of post-hemorrhagic cyst].
The authors describe a case of spontaneous intracerebral haematoma treated conservatively. After three months a large posthaemorrhagic cyst of the brain was found in the sensorimotor area. The authors suppose that in case of surgical treatment the course of the disease and its sequelae would have been much milder. The interest shown by neurologists in the problem of spontaneous intracerebral haematoma seems to be too low and the possibility of surgical treatment is not mentioned in the neurological literature.
Growth factors in mouse mammary cell interactions in vitro.
Paracrine interactions may be important in homeostasis of mammary gland. We have previously reported that normal mammary epithelial cells and stromal cells stimulate the growth of mammary tumor cells in 3-dimensional cultures in collagen gels. We now describe the ability of EGF, TGF beta, bFGF, aFGF, and PDGF to directly affect growth of tumor cells in 3-dimensional cultures in collagen gels. In addition, we assessed the ability of neutralizing antibodies against each growth factor to disrupt interactions between normal mammary cells and mammary tumor cells. Only bFGF and PDGF directly stimulated growth of the mouse mammary tumor cells. However, neither anti-bFGF nor anti-PDGF abrogated the stimulation of tumor cells by normal mammary epithelial cells or normal mammary stromal cell.