[The 65th anniversary of Professor Vladimír Galanda, C. Sc].
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Biomedical subjects
Publications and source records attributed to J Buchanec.
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Acetylsalicylic acid in a single dose of 10 mg/kg orally affected the skin temperature of the hand of febrile and afebrile children. In the afebrile group the rise of skin temperature after 1 hour (p less than 0,05) and 2 hours (p less than 0.01) was not accompanied by significant change of the sublingual or axillar temperature. In the febrile group the rise of the skin temperature of the 3rd finger after 1 hour (p less than 0,001) and 2 hours (p less than 0.001) was accompanied by a significant decrease of the sublingual and axillar temperature and by a decrease of pulse rate. The changes were more pronounced after 1 hour after administration of the drug. Similarly, the acetylsalicylic acid enhanced the relative blood flow through the skin of the finger of hand.
For the assessment of ureteral urine passage in children sequential scintigraphy with an analyzing system was used. Through the proper division of the time of examination into short time intervals the information on the areal distribution of urine was obtained, dependent on time. After demarcation of the spheres of interest by light-pen, the level of radioactivity was followed continually in a form of curves. Information for the assessment of etiopathogenesis of the disease was selected from the memory system of the device. Through the radioisotope examination also the dynamic changes have been recorded, not visible in excretion urograms, or only presumable from them. The method of examination described can help to assess the functional importance of morphological findings.
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The results of sequential scintigraphy of the kidneys of 22 children with orthostatic proteinuria and of 25 patients with nephritis or nephrotic syndrome, respectively, have been evaluated. At particular time intervals significant differences have been found between the two groups. On the basis of the visual method of evaluation of scintiscans and by bilateral comparison the authors conclude that in children with orthostatic proteinuria the frequency of asymmetry of the kidneys was significantly higher. These changes were most likely due to spasms or other disturbances of the function of excretory urinary passages in the calyx-pelvis system as responses to unfavourable emotional inpulses (intravenous application of the substance, etc.) and to the sitting position during the examination.
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