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Biomedical subjects

J Buch

Publications and source records attributed to J Buch.

At least 55 records · Page 3Linked to original sources
PubMed1980

Interrupted aortic arch in two siblings.

Two siblings with identical malformations consisting of complete interruption of the aortic arch, type B, ventricular septal defect, patent ductus arteriosus and anomalous origin of the right subclavian artery are described. Five other unrelated patients with interrupted aortic arch have been investigated in the years 1971--79. Of their 6 siblings, one had a coarctation of the aorta, while 5 were normal. Together with future reports this may help us to elucidate the genetics of this entity and may improve genetic counselling.

Aorta, Thoracic↗
PubMed1980

Correlation between changes in systolic time intervals and left ventricular end-diastolic diameter after preload reduction. Non-invasive monitoring of pharmacological intervention.

In order to measure the effect of a decrease in preload on systolic time intervals and left ventricular end-diastolic diameter (LVEDD) measured by echocardiography, eight healthy young subjects were given 40 mg frusemide intravenously. The pre-ejection period index (PEPI) increased and the left ventricular end-diastolic diameter decreased. A correlation between delta PEPI and delta LVEDD was shown. Using changes in systolic time intervals in the evaluation of changes in contractility it is important to correct for changes in preload. For normal subjects it is suggested that the relation between delta PEPI and delta LVEDD as a percentage of the mean values should be used for this correction. A method is suggested for estimating the changes in pre-ejection period index induced by changes in left ventricular end-diastolic diameter.

Adult↗
PubMed1980

Children's response to various local fluoride treatments.

The aim of the study was to evaluate children's responses to four different gel tray systems and their preference to gel treatment twice a year versus fortnightly fluoride rinsing. For the study 91 children attending third grade (10-11 years) were divided into 3 groups and 119 children attending seventh grade (14-15 years) into 4 groups. The children were treated with a neutral 2% sodium fluoride tixotropic gel by means of one of the following trays: A. Air Cushion Fluoridator B. Centrays C. An individually constructed tray made of impression material (Citricon) D. An individually constructed tray made from soft acrylic. After treatment the children's response toward the treatment was evaluated by means of interviews. The majority of the children preferred gel tray treatment to fortnightly mouth rinsing (p less than 0.0003). Disposable trays were less acceptable than the individually made trays or the Air Cushion Fluoridator. However, all trays were tolerated for 15 minutes by all children. Cost analysis showed that the difference in expense using the various trays decreased as the number of treatments of the single individual increased.

Adolescent↗
PubMed1980

Transient ECG changes during acute attacks of pancreatitis.

Information on the prevalence of ECG abnormalities in patients with acute pancreatitis together with pertinent simultaneous laboratory data have been missing. This prospective study was undertaken in order to clarify these points. 54 patients with 72 acute attacks of pancreatitis were examined. 31 patients (57%) had transient ECG abnormalities. The ECG changes consisted mainly of unspecific T-wave changes (25 cases) and accelerated atrial or nodal rhythms (8 cases). The ECG changes were more common in patients with biliary etiology (80%) than in patients with alcoholic etiology (49%), probably partly due to the higher age of the patients with biliary disease. The laboratory data did not give any clue to the cause of the ECG changes. The authors believe that the ECG changes may be due to underlying ischemic heart disease unmasked by the stress of acute pancreatitis, and/or imbalance of the autonomous nervous system.

Acute Disease↗
PubMed1979

The value of serum fibrinogen degradation products in the differential diagnosis between acute myocardial infarction and pulmonary embolism.

Serum-FDP was measured in 148 patients with AMI or pulmonary embolism within 48 hours of the onset of symptoms or within 48 hours of the admission to hospital. Within 48 hours of the hospitalisation 14.6% of the patients with AMI Rand 81.8% of the patients pulmonary embolism showed a serum-FDP elevation to over 10 units/ml. The use of the analysis is limited by the time which elapses until the result is available, by the short duration of the serum-FDP elevation and by the lack of specificity of the examination.

Adult↗
PubMed1979

Canrenoate--a spironolactone metabolite. Acute cardiac effects in digitalized patients.

Canrenoate (Soldactone)--a spironolactone metabolite for intravenous use--has recently been suggested as a specific antidote in patients suffering from digitalis intoxication. Theoretically, this would imply that canrenoate could counteract the effect of digoxin. The influence of canrenoate on inotropy in 12 digitalized patients was investigated by measurement of sytolic time intervals. Canrenoate improved the left ventricular contractility, since both preejection period (PEP) and the ratio between PEP and left ventricular ejection time (PEP/LVET) decreased significantly. The maximal changes in controlled atrial fibrillation, canrenoate had no effect on ventricular rate, whereas atropine increased the ventricular rate significantly.

Aged↗
PubMed1978

Serum digoxin and empiric methods in identification of digitoxicity.

A prospective study of consecutive patients admitted to a medical service was undertaken to evaluate the prevalence of cardiac digitalis toxicity and the relative diagnostic values of serum digoxin versus an empiric method, based on calculations of digoxin dose in relation to kidney function and body weight. Of 711 patients admitted, 109 were treated with digitalis on admission. Sixteen of the patients developed cardiac arrhythmias consistent with digitalis intoxication. Five of these, none with serum digoxin above 1.6 ng/ml, were not toxic. The remaining eleven patients, all with serum digoxin levels above 1.6 ng/ml, were either definitely or possibly toxic. A similar borderline between intoxicated and nonintoxicated patients could not be established on the basis of calculations based on body weight and renal function. In all cases in which suspicion of digitalis intoxication was raised, serum digoxin measurements could discriminate between the toxic and the nontoxic patients.

Aged↗