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Biomedical subjects

J Brismar

Publications and source records attributed to J Brismar.

At least 73 records · Page 4Linked to original sources

Therapeutic embolization in the external carotid artery region.

Therapeutic transcatheter embolization with spongostan in the region of the external carotid artery has been employed in 17 patients, in some of them on several occasions. The technique is presented and different means of avoiding complications are discussed in detail. Embolization has been used preoperatively and as the single mode of treatment of ENT tumours or meningeomas, and also as the only treatment in arteriovenous malformations. The technique has proven particularly useful in preoperative de-arterialization of ENT tumours when surgery follows in 1 to 2 days. In cases with arteriovenous shunts, a subjective improvement has been achieved.

Adolescent↗

Aseptic thrombosis of orbital veins and cavernous sinus. Clinical symptomatology.

Occlusion or thrombosis of the superior ophthalmic vein or of the cavernous sinus is an unspecific finding that may be secondary to different disorders such as tumours of the skull base or nasopharynx. Sometimes, however, no underlying disorder is found in spite of an extensive clinical and radiological evaluation. Eight such cases are here presented. Similar cases have previously been described, both as examples of the Tolosa-Hunt syndrome and as aseptic cavernous sinus thrombosis. The literature on these two disorders is reviewed and different diagnostic criteria discussed.

Aged↗

Thrombosis of the intraorbital veins and cavernous sinus.

Eight cases with phlebographic appearances consistent with aseptic thrombosis of the cavernous sinus or of the posterior part of the superior ophthalmic vein are presented. The clinical course is briefly described and the phlebographic findings and possible differential diagnoses discussed. Even if recent methods may obviate the need for phlebography in the demonstration of orbital tumors in certain cases, the possibility of intraorbital or cavernous sinus thrombosis constitutes an important indication for phlebography.

Adult↗

Cervical myelography with metrizamide.

In 177 patients 190 cervical myelographies were performed, 52 after cervical and 138 after lumbar puncture. While the last-mentioned technique may be considered as the safest, the first-mentioned appears to cause less adverse reactions and also offers films of higher quality. The cooperative ability of the patient as well as the shape of the spine must be considered for selecting the site of puncture. Films are obtained permitting high diagnostic accuracy with regard to lesions involving root sleeves and to the presence of intramedullary or extramedullary lesions, in particular protrusions and disc herniations.

Humans↗

Cisternography with metrizamide and hypocycloidal tomography.

Cisternography with metrizamide (Amipaque) and hypocycloidal tomography was found to depict cisternal anatomy with detail and precision not obtainable with any other technique. Clinical tolerance is comparable to that of encephalography if suitable precautions are followed. All side effects observed had disappeared 36 hours after injection, and no delayed noxious effects were recorded. This method offers a simple, rapid and precise technique for depicting cisternal anatomy and requires no equipment other than a tilting multidirectional tomographic unit.

Humans↗

Radiation necrosis of the brain. Neuroradiological considerations with computed tomography.

In cases with radiation necrosis of the brain, conventional neuroradiological examinations usually demonstrate only an avascular mass lesion impossible to differentiate from intracerebral tumor or hemorrhage. Computed tomography, performed in addition to angiography in three cases, consistently demonstrated the radiation necrosis as a low density area exhibiting enhancement following infusion of contrast medium. The importance of recognizing radiation necrosis as a differential diagnosis to brain neoplasm is emphasized.

Adolescent↗

Unilateral endocrine exophthalmos. Diagnostic problems in association with computed tomography.

Swollen orbital extraocular muscles may mimic an orbital apex tumor on computed tomography. In five of our patients, in spite of highly suggestive findings on CT scanning, indicating the presence of an orbital apex lesion, the correct diagnosis proved to be endocrine exophthalmos. The value of complementary CT projections and of orbital ultrasonography to assist in the differential diagnosis is discussed, and the additional contribution of orbital phlebography for the confirmation of lesions in the orbital apex is emphasized.

Adult↗

Spontaneous carotid-cavernous fistulas. Clinical symptomatology.

The symptomatology in six cases with spontaneous carotid-cavernous fistulas is discussed. All six patients presented with exophthalmos, dilated veins, pain and restriction of ocular movements. In four patients a bruit was found objectively as well as subjectively, four patients exhibited an increase of the intraocular pressure and in three cases vision was impaired. Of special interest is the finding that discrete symptoms such as venous congestion and slight pain appeared early in the course of the disease in all patients, and that in some of the patients an increase in intraocular pressure as well as disturbances in ocular motility were diagnosed long before the appearance of the exophthalmos.

Adolescent↗

Orbital phlebography in evaluation of the cavernous sinus and adjacent basal veins of the skull.

Frontal vein phlebography has proven to be of great diagnostic value in the evaluation of pituitary tumours and of lesions in the vicinity of the sella turcica. It permits the diagnosis of venous thrombosis; similar phlebographic changes may be the only positive radiologic finding in cases with malignant tumour of the skull base. Phlebography is thus to be recommended as an early method to be used in possibly malignant lesions at the skull base.

Adult↗

Persistent hypoglossal artery, diagnostic criteria. Report of a case.

After a brief racapitulation of the embryology of the vertebrobasilar arterial system, one new case (the 26th) with a persistent hypoglossal artery is presented. As in this case a well developed posterior communicating artery existed, new diagnostic criteria have been formulated.

Basilar Artery↗

Spontaneous carotid-cavernous fistulas: phlebographic appearance and relation to thrombosis.

Six consecutive cases with spontaneous carotid-cavernous fistulas were examined with orbital phlebography and bilateral carotid angiography. One of the fistulas was fed only by one internal carotid artery, 1 only by the accessory meningeal branch of the maxillary artery, while 4 were supplied by external as well as internal carotid arteries. The findings at phlebography seem to be characteristic. Thrombosis was demonstrated in all 6 cases. Different mechanisms for the genesis of thrombosis in association with carotid-cavernous fistulas are proposed. Alternative therapy methods are discussed.

Adolescent↗

Complications of orbital and skull base phlebography.

Two complications, one in association with frontal vein phlebography and one in association with inferior petrosal sinus phlebography, are presented. Possible mechanisms for complications are discussed. It is concluded that a significant risk exists in association with inferior petrosal sinus phlebography, particularly in association with vascular disorders of the skull base, while the risk in association with orbital phlebography after frontal vein puncture is minimal if compression of the jugular veins is omitted.

Aged↗

Metrizamide cisternography with hypocycloidal tomography: preliminary results.

Metrizamide (Amipaque), a nonionic water soluble contrast agent, has been shown to be safe and efficacious for lumbar myelography. Clinical trials of cervical, thoracic, and even intracranial examinations have produced good results. Despite an inherent neurotoxicity, significant complications have been quite rare, and patient tolerance in general is remarkably good. Preliminary results of metrizamide cisternograms using hypocycloidal tomography are presented to illustrate the anatomic detail which can be demonstrated using this technique.

Humans↗

CSF enhancement for computerized tomography.

Metrizamide cisternography, combined with hypocycloidal tomography, has been performed in 12 patients with possible posterior fossa or parasellar mass lesions with finely detailed images of the basal cisterns resulting. Computed tomography was performed in nine of these patients and produced exceptional images of the cisternal anatomy. The technique of cerebrospinal fluid enhancement may be efficacious in identifying small basal masses not shown with conventional computed tomography, and thus may form an important complement to enhancement by intravenous injection of contrast medium.

Brain Neoplasms↗