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Biomedical subjects

J Bourke

Publications and source records attributed to J Bourke.

At least 37 records · Page 2Linked to original sources

Epicardial repolarization mapping in man.

A simple method was developed for recording epicardial monophasic action potentials intraoperatively in man. Potentials were recorded rapidly and reliably from multiple epicardial sites using a hand-held probe. The feasibility of repolarization mapping was assessed in 30 patients. It was possible to record technically adequate signals from most left ventricular and posterior right ventricular sites (success rates 72% and 61%, respectively), but it was more difficult to achieve satisfactory recordings over the free wall of the right ventricle (success rate 36%). The onset of cardiopulmonary bypass resulted in a transient rise in action potential duration of approximately 30-40 ms in the first minutes of bypass. An approximate steady state was achieved thereafter. Reproducibility of the method was assessed by mapping a small number of sites repeatedly. The 95% confidence limits for an estimate of repolarization time, based on a single potential, were +/- 21 ms. With 4 probe applications at each site, the confidence limits of the estimated site mean were reduced to +/- 8 ms. Based on this approach, statistically significant differences between sites were demonstrated in 9 of 10 patients, confirming that the method is sensitive enough to provide information on regional differences in repolarization. Intraoperative epicardial repolarization mapping has been shown to be a practical possibility. The technique holds promise as a means of assessing the role of dispersion of repolarization in arrhythmogenesis in man.

Action Potentials↗

Percutaneous removal of a fractured right heart catheter from the apex of the right ventricle.

A 58-year-old woman underwent right and left heart catheterization for suspected ischaemic heart disease with ventricular tachycardia. During the procedure a Bourassa catheter fractured and lodged at the right ventricular apex. Under general anaesthesia and radiographic screening the fragment was removed using a bronchoscopy biopsy forceps via the jugular vein after other methods had failed. This case highlights the need for familiarity with several techniques for the removal of such fragments.

Cardiac Catheterization↗

Reward employees, achieve goals with incentive compensation.

Incentive compensation, rewarding employees financially for extraordinary performance, can be a motivational tool for healthcare organizations. This method of compensation uses a financial reward as an incentive for executives to achieve certain predetermined, agreed-upon goals. Incentive compensation provides two advantages for the healthcare organization--it provides a mechanism to maximize organizational productivity and it gives executives a means to achieve greater compensation.

Employee Incentive Plans↗

Mast cells in pulmonary haemosiderosis.

A case of childhood pulmonary haemosiderosis with a fourfold increase in mast cells in the lung is described. This finding is discussed in relation to the pathogenesis of the disease. Comparison is made with controls, and the use of disodium cromoglycate is advocated.

Cell Count↗

Fifty years survival after cervical fracture and fusion.

A patient who survived for 50 years after two cervical injuries is described. Among other effects he showed remarkable compensatory changes in the vertebrae above and below a cervical fusion operation. He also developed a meningeal pseudocyst following lumbar laminectomy. The history and pathological findings are considered to be instructive.

Aged↗