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Biomedical subjects

J Bourgeois

Publications and source records attributed to J Bourgeois.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

[Anatomical study of the kidneys of newborn infants dying after a septic state].

Over a 6 years period, 51 autopsies have been performed in infants dead after severe sepsis. One third of them had renal damages, consisting mainly in haemorrhagic infiltration. Pathological and clinical data are not always well correlated, but some parameters may enhance a poorer renal prognosis, such as the duration of shock and anuria, or exchange transfusion. The clinical presentation of the infection and the encountered germs are the same in both groups, with or without renal damage. A better management of intensive haemodynamic cares in these neonates increases their survival rate and raises the problem of chronic renal failure or hypertension in this situation. It seems very useful to state precisely the surveillance and protection of the renal function in such patients.

Acute Kidney Injury↗
PubMedDate not supplied

[Necrotizing enterocolitis and cytomegalovirus infection (author's transl)].

During an 18-month period, 11 cases of necrotizing enterocolitis (NEC) were diagnosed in infants treated in Neonate Department. This represents 1% of total admissions. Six cases occurred during hospitalization. Clinically, the disease took three different forms: surgical form, medical form responding well to exclusive parenteral feeding and isolated haemorrhagic form, which deserves discussion. Seven of these infants had cytomegalovirus (CMV) infection. NEC accounted for 22% of clinical symptoms in CMV infection. These data suggest that the cytomegalovirus may act as aggravating factor in NEC.

Cytomegalovirus Infections↗
PubMedDate not supplied

[Course of inflammatory and nutrition proteins in bacterial infections in newborn infants].

A study of 214 neonates (with 87 premature infants) reveals that C-reactive protein (CRP), orosomucoid and prealbumin are the most interesting proteins for the diagnosis of neonatal sepsis and for studying its follow-up. Orosomucoid is high in 85% of bacterial infections and CRP in 75%. Early type strep B infections give often false negative results. The evolution of CRP and of prealbumin corresponds to the effects of treatment and the evolution of orosomucoid is parallel to the healing of the patients. The ratio orosomucoid/prealbumin allows an earlier appreciation of the healing.

Bacterial Infections↗
PubMedDate not supplied

[Neonatal ulcero-necrotizing enterocolitis and aspergillosis].

A preterm infant of 33 weeks of gestation and very small birthweight 1040 g developed on the third day of life a necrotizing enterocolitis with spontaneous perforation. Peritoneal fluid and small bowel meconium was cultured and revealed Aspergillus Niger. The literature is reviewed with seven cases of aspergillosis in newborn period. The infant is dead on the tenth day of life from periventricular haemorrhage. Necropsy was performed and revealed no secondary aspergillosis localisation.

Aspergillosis↗
PubMedDate not supplied

[Acquired neonatal herpes].

The authors report a case of neonatal herpes simplex infection with favourable outcome, without any sign of meningo-encephalitis or dissemination. The child was given antiviral treatment with Acyclovir from the first day of rash. Vesicle scraping and a complete serologic study of both child and mother proved infection was due to herpes simplex virus type I, transmitted to the neonate during primary maternal infection with gingivostomatitis beginning on the day of delivery. The different routes of postnatal contamination of the neonate by herpes virus and the risks of dissemination are reviewed. The importance of preventing contamination and dissemination of a known herpetic infection in maternity-hospitals and in nurseries for newborns is emphasized. Antiviral treatment should be used in all neonates with localized herpetic infection.

Female↗
PubMedDate not supplied

[Hyponatremia and theophylline in very low birthweight premature infants].

A retrospective study of the occurrence of hyponatremia (i.e. less than 135 mmol/l) was carried out in 17 control preterm neonates and 25 infants treated with theophylline. These infants had a birthweight lower than 1,301 g and a gestational age less than 36 weeks. Despite a similar sodium and water intake in both groups, hyponatremia was detected at the age of 7-8 days in 37% infants treated with theophylline and none of the control infants. Their mean weight loss was 11% with theophylline and 5% in the controls. These data suggest that theophylline may play a role in the occurrence of hyponatremia of very low birthweight infants.

Apnea↗