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Biomedical subjects

J Boucher

Publications and source records attributed to J Boucher.

At least 73 records · Page 4Linked to original sources
PubMed1977

Hand preference in autistic children and their parents.

Hand preference was tested in groups of between 40 and 50 autistic children and in sex-, age-, and ability-matched controls. Results were also compared with existing findings on normal children. Small differences occurred between the groups in the directions which would be predicted on the assumption that mental subnormality is associated with delayed development of normal patterns of handedness, and on the hypothesis that autistic children as a group will show a persistent slightly increased tendency to use the left hand. Parents of the autistic group were also assessed for handedness. Contrary to the prediction of slightly increased sinistrality in this group of subjects, some indication of increased dextrality occurred. Results were discussed in relation to possible genetic factors in the etiology of autism.

Adolescent↗
PubMed1976

Articulation in early childhood autism.

Using a standardized articulation test, comparisons were made between the articulation of autistic children and (1) a group of predominantly subnormal language matched controls; (2) developmental receptive dysphasic controls. The autistic children's articulation was significantly superior to that of both control groups. The findings are discussed in relation to differences in the pattern of language impairment in the three groups.

Adolescent↗
PubMed1976

Memory deficits in early infantile autism: some similarities to the amnesic syndrome.

Autistic children were compared with control children on tasks in which retention was tested by different methods. In three tests of recall, using named pictures, written words and spoken words as test stimuli, autistic children were impaired in comparison with age-matched normal children and with controls matched for verbal ability. In one test of forced-choice recognition of pictures, autistic children were impaired in comparison with ability-matched controls. In three tests of cued recall, using named pictures, written words and spoken words as test stimuli, and acoustic, graphemic and semantic cues, autistic children were not impaired in comparison with normal age-matched controls. In one test of paired-associate learning using non-related word pairs as test stimuli autistic children were not impaired in comparison with normal age-matched controls. These experimental paradigms were similar to some that have been used to investigate the amnesic syndrome in man. Thus findings on paired-associate learning differ in autistic and amnesic subjects, but findings on recall, recognition and cued recall are comparable. A possible parallel between autism and amnesia is discussed.

Acoustic Stimulation↗
PubMed1974

Epstein-Barr virus infection in the neonatal period and in childhood.

In an attempt to detect and characterize congenital, neonatal and early childhood EBV infections, a prospective sero-epidemiological study was undertaken in 112 newborn infants and their mothers, 25 additional newborns undergoing exchange transfusion, 114 randomly selected hospitalized infants aged 0 to 3 years, and 109 siblings and parents of these infants. Leukocyte culture was attempted in all the newborns and in 25 pre- and post-transfusion.The findings of EBV seroconversion in six patients without clearly apparent illness, infectious mononucleosis in only one case with significant EBV antibody rise, seroreversion in three cases in early childhood, higher newborn than maternal EBV antibody titres in three cases and the establishment of two permanent lymphoblastoid cell lines from newborns following exchange transfusion raise the possibility of abortive primary EBV infection in early life. Congenital or neonatal infections following exchange transfusions, however, could not be substantiated with certainty since the EBV antibodies did not persist at follow-up except possibly in two cases. Parenteral transmission of the EB virus by exchange transfusion at birth is probably prevented by the presence of EBV antibodies in either donor or recipient.

Antibodies, Viral↗
PubMedDate not supplied

Structural patterns in conversations with a woman who has autism.

The experience of conversing with a person who has autism is often described as unsatisfactory. This article offers some suggestions as to why that might be. Conversation between an adult diagnosed as autistic and a researcher was transcribed and analyzed using the methodology of Conversation Analysis. The analysis highlights differences in conversational style between the two participants based on features such as topic movement, topic maintenance, repairs, interference from earlier structures and common collocations, overlaps, latching, and pauses. It is suggested that many of the features of the subject's talk which result in an overly repetitive style may be cognitively motivated.

Adult↗
PubMedDate not supplied

Relationships between symbolic play, functional play, verbal and non-verbal ability in young children.

It is well established that certain aspects of play in young children are related to their emerging linguistic skills. The present study examined the relationships between functional play, symbolic play, non-verbal ability, and expressive and receptive language in normally developing children aged between 1 and 6 years using standardized assessment procedures, including a recently developed Test of Pretend Play (ToPP). When effects of chronological age were partialled out, symbolic play remained significantly correlated with both expressive and receptive language, but not with functional play or non-verbal ability; and functional play was only correlated significantly with expressive language. It is concluded that ToPP will provide practitioners with a useful way of assessing symbolic ability in children between the ages of 1 and 6 years, and will contribute to the assessment and diagnosis of a number of communication difficulties, and have implications for intervention.

Child↗
PubMedDate not supplied

Metamemory in children with autism.

Five experiments are reported comparing metamemory abilities in children with autism, age- and language-matched mentally retarded children, and language-matched young normal controls. The mean language age of the participants in Experiment 1 was approximately 6 years, in Experiments 2, 3, and 4 approximately 8 years, and in Experiment 5 approximately 9 years. All the children were given one or more false belief tests. Experiment 1 assessed the children's understanding that a task variable (list length) and a person variable (age) will affect their own and others' performances on an immediate auditory-verbal recall task. Experiment 2 assessed the ability to utilize category cues in a picture recall task. Experiments 3 and 4 assessed the ability to verbalize strategies used in a memory span test and in one retrospective and two prospective memory situations. Experiment 5 assessed the children's knowledge and understanding of another person's memory. On the basis of available evidence and theory, we predicted that the children with autism would be impaired on all the metamemory tasks and that impairment would be associated with failure on tests of false belief. Our predictions were not supported. The children with autism were not impaired on any of the metamemory tasks, although they were less likely than controls to make spontaneous use of memory strategies involving other people. Unexpectedly few of the children failed the false belief tasks. These results are discussed in relation to theories concerning primary psychological deficits underlying autism.

Adolescent↗