Pituitary peptides with direct action on the metabolism of carbohydates and fatty acids.
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Biomedical subjects
Publications and source records attributed to J Bornstein.
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This first-ever study of the use of restraint on psychiatric patients in Israel sought to determine the dominant motivations in the decision to use restraint, which patients were most likely to be restrained, and whether there was a consistent policy on the matter. A survey of the official records of every instance of restraint during one month in the closed wards of all government psychiatric hospitals, supplemented with interviews, revealed that 14.2% of the study population had undergone restraint. The declared reasons were conventional, i.e. violence, disturbed behaviour, etc. Undeclared was an interaction between patients and staff, both the most professional and the less skilled, which surprised the authors and requires more investigation. Some subgroups, e.g. women and certain immigrant groups, were restrained markedly more frequently than other groups. No consistency of policy was found. Overall, much of the restraint applied is deemed unnecessary and recommendations are made for its reduction.
Nine patients with completely perforating intrauterine contraceptive devices are presented. In all cases, the device was removed by explorative laparotomy. In eight out of the nine women, the device was found to be embedded in the omentum or vesical peritoneal plica. The advantages of explorative laparotomy over laparoscopy or colpotomy are emphasized.
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PURPOSE: Uterine leiomyomata alone are an infrequent cause of infertility. We presumed that--since the smaller the uterine size at the time of myomectomy, the greater the chances of subsequent conception--diminishing the preoperative tumor size in infertile patients with large leiomyomata prior to myomectomy should be beneficial. PROCEDURE: Decapeptyl (D-Trp6-LHRH) depot 3.2 mg was administered for a period of 3-6 months to 23 infertile women. No causes of infertility were found in these patients except for uterine leiomyomata. In 10 of the 23 patients conservative myomectomy was added to Decapeptyl treatment. FINDINGS: Following Decapeptyl treatment an average decrease in uterine volume of 57% (range: 22%-86%) was observed in all patients. In ten of the 23 patients conservative myomectomy was added to Decapeptyl treatment resulting in a further 16% decrease in uterine volume. Uterine regrowth following Decapeptyl and myomectomy was found to be significantly lower (P < 0.01) when compared with cases treated with Decapeptyl alone. Five of the ten patients treated by Decapeptyl and myomectomy achieved successful pregnancies and delivered. Among the women treated with Decapeptyl without myomectomy, only one patient conceived. CONCLUSIONS: From these findings it may be concluded that combined GnRH and myomectomy is the treatment of choice for infertile women with large uterine leiomyomata.