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J Borkenstein

Publications and source records attributed to J Borkenstein.

34 records · Page 2Linked to original sources
PubMed1976

[Considerations on the information content of diagnostic tests (author's transl)].

The value of a diagnostic test lies in its ability to support the doctor's efforts to detect a certain disease. The aim is to achieve the highest possible probability that the disease is correctly diagnosed by means of the test. Doctors are not always aware of the extent to which a test can contribute to the final diagnosis. This contribution, the information content of the test, can be calculated by various algebraic manipulations. An example (carcinoembryonic antigen) is given, which demonstrates the significance of certain terms such as true and false positive results or likelihood and, moreover, the application of Baye's theorem.

Bayes Theorem↗
PubMed1976

[The effect of nitroglycerine medication on the arterial oxygen pressure in obstructive lung disease].

Nitroglycerine gains increasing interest because of its favourable hemodynamic effects in patients with left heart failure, especially in those with coronary heart disease. The drug-induced vasodilatation and lowering of pulmonary arterial pressure, is followed by a redistribution of lung perfusion which occasionally may be deletarious. It is shown that in patients with obstructive lung disease, a significant drop in arterial oxygen tension may be observed. This could be due to increased perfusion of the lung, without a concommitant augmentation of ventilation, which results in an increase of right to left-shunt.

Adult↗