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J Bordas

Publications and source records attributed to J Bordas.

66 records · Page 4Linked to original sources
PubMed1978

[Bronchofibroscopy. 6 questions, 6 fundamental answers].

The authors report the aims, methods, techniques of sampling and the tolerance of broncho-fibroscopy, correlating literature and their personal experience of a thousand examinations. They consider it a very simple examination which without any inconvenience can be used in very serious cases as well as for out-patients. They insist on the technique of biopsy and directed aspiration and demonstrate that with experience the yield of the method can be improved. They conclude by saying that a histo-cytological diagnosis can be made in 95% of cases of bronchial cancers. In their experience, tolerance to this examination is always very good.

Biopsy↗
PubMedDate not supplied

X-ray solution scattering studies on vinblastine-induced polymers of microtubule protein: structural characterisation and effects of temperature.

We report here on X-ray solution scattering and electron microscopy studies of microtubule protein in the presence of the antimitotic drug, vinblastine. In buffer conditions used for microtubule assembly, vinblastine caused the formation of coil-like structures. The coils appeared to be made up of two protofilaments. Details of the structure and behaviour of coils in solution were obtained from interpretation of their solution scattering patterns. Upon increasing temperature from 4 to 37 degrees C the pitch of the coils increased from 25.92 to 26.96 nm. However, little change was observed in their mean diameters (38.46 and 38.45 nm, respectively). Increasing the temperature also favoured increased formation and/or elongation of the coils. The effect of temperature on the pitch was fully reversible. Vinblastine-induced assembly of pure tubulin also showed the formation of coils. However, these coils appeared to consist of only one protofilament. Their mean diameters (38.35 nm) were similar to those of the coils formed from microtubule protein.

Animals↗
PubMedDate not supplied

Laparoscopic treatment of acute biliary pancreatitis.

UNLABELLED: Laparoscopic cholecystectomy (LC) has become the standard treatment of gallstones. Application of LC in certain complications of biliary stones such as acute biliary pancreatitis (ABP) is not well defined. 10-30% of patients with ABP present associated bile duct stones, and the realization of a preoperative ERCP has been routinely proposed. Nevertheless, this examination may be unnecessary in most patients. AIM: To investigate the applicability of laparoscopic surgery for treatment of ABP. MATERIALS AND METHODS: Between Jan-1992 and June-1995, 368 patients were prospectively evaluated for LC, 274 for indications other than ABP. (Group I, LC) and 91 as a consequence of ABP. (Group II, ABPxL). ERCP was indicated when ultrasonography showed a dilated bile duct (> 8 mm) or when the liver function test (LFT) presented high scores. Age, sex, operative time, incidence of bile duct stones, postoperative stay and morbimortality were evaluated. RESULTS: The two groups were well matched for age, sex and associated medical risk factors. There were no differences in the operative time, conversion rate or postoperative morbidity (10% vs 10%). ERCP was performed in 25 patients in Group II and bile duct stones were found in 12 cases. In all cases an intraoperative cholangiography was performed, and in 6 patients, bile duct stones were removed by laparoscopic means. Three patients were converted to open surgery on finding duct stones which could not be treated by laparoscopic means. Mean postoperative stay was significantly longer in Group II than in Group I. In two cases, pancreatic pseudocyst was attempted with a laparoscopic approach. CONCLUSIONS: Definitive treatment of ABP could be accomplished effectively by laparoscopy, with selective indication of ERCP.

Acute Disease↗