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Biomedical subjects

J Bonnet

Publications and source records attributed to J Bonnet.

At least 217 records · Page 12Linked to original sources
PubMed1975

Study of the role of the acceptor stem in the interactions between tRNAs and aminoacyl-tRNA synthetases.

Several studies have clearly demonstrated that the end of the acceptor stem was a very important area determining the aminoacylation properties of tRNAs. However the attempts to measure the contribution of this region to the binding of tRNAs to aminoacyl-tRNA synthetases have led to contradictory results. We report here the stepwise degradation of yeast tRNA-Phe and tRNA-Val from their 3' terminus, up to the seventh nucleotide : the affinity of each of the degraded-tRNA for their cognate aminoacyl-tRNA synthetase was compared to that of intact tRNA and it was found that these affinities are not significantly decreased when compared to those of the intact tRNAs.

Amino Acyl-tRNA Synthetases↗
PubMed1975

Fracture of the clavicle.

In the treatment of fractures of the clavicle the generally accepted principles of fracture treatment should be observed, viz: X-rays in two projections at least, anatomical reduction and fixation stable enough to withstand exercising. Treatment with just a sling is adequate in children up to 14 years of age and also in older patients with only slight displacement. Surgical reduction and fixation with a Kirschner wire is to be preferred in patients older than 14 years with shortening by more than 1 cm or with severe displacement in another direction, and in cases of comminuted fractures. Patients with such fractures in whom operation is contra-indicated should be treated with an abduction-tractionbandage. The dorsal pad should be abandoned.

Adolescent↗