Search PubMed⌕ Search

Biomedical subjects

J Bonnar

Publications and source records attributed to J Bonnar.

At least 145 records · Page 8Linked to original sources
PubMed1973

Blood coagulation changes during mid-trimester abortion induced by prostaglandin F2 alpha.

Serial studies on the coagulation system were made during second-trimester abortion induced by extra-amniotic, intra-amniotic, vaginal, and intravenous prostaglandin F(2)alpha. No significant changes were found in the prothrombin time, partial thromboplastin time, or levels of fibrin-fibrinogen degradation products. An increase in the activity of factor X occurred with all routes of administration; the activity of factor VIII increased during extra-amniotic, vaginal, and intravenous administration; factor V activity increased during extra-amniotic and vaginal administration; and the activity of factor VII-X complex increased slightly at the time of abortion with all methods.The findings suggest that though prostaglandin induction of second-trimester abortion produces changes in the coagulation system the effects are much less than those which accompany induction of abortion by hypertonic saline or abdominal delivery in late pregnancy.

Abortion, Induced↗
PubMed1973

Coagulation changes during termination of pregnancy by prostaglandins and by vacuum aspiration.

Serial studies on coagulation factors were performed on 12 patients having termination of mid-trimester pregnancy by extra-amniotic prostaglandin F(2)alpha and 11 patients terminated by vacuum aspiration during the first trimester. A significant change in the activity of factors V, VII and X, VIII, and X, and a decrease of the prothrombin time and platelet count were found with prostaglandin termination but no such changes occurred during vacuum aspiration. These findings suggest that the coagulation system is activated during induction of mid-trimester abortion with extra-amniotic prostaglandin F(2)alpha. This is probably related to the physiological changes in the coagulation mechanism which occur by the second trimester of pregnancy. Termination of pregnancy in the mid-trimester may, however, be expected to give rise to defective blood coagulation and thromboembolic complications.

Abortion, Induced↗
PubMed1971

Abdominal wound dehiscence after caesarean section.

In a series of 2,175 patients delivered by caesarean section a dehiscence of the abdominal wound occurred in 50. Wound dehiscence was eight times more common with a vertical incision than with a low transverse incision of the abdominal wall; with the vertical incision the incidence of partial and complete dehisence was 2.94% and with the low transverse incision no complete dehiscence occurred and the incidence of partial dehisence was 0.37%. The increased use of the low transverse incision would greatly reduce the serious complication of wound dehiscence after caesarean section.

Adult↗