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Biomedical subjects

J Bonet

Publications and source records attributed to J Bonet.

At least 55 records · Page 3Linked to original sources

[Athero-embolic nephropathy. Report of 2 cases].

Two cases of athero-embolic nephropathy unrelated with known precipitating factors such as aortic surgery, angiography, anticoagulation or pharmacological fibrinolysis are reported. In one, the histological study additionally disclosed endo-extracapillary proliferative glomerulonephritis. Hypocomplementemia or hypereosinophilia, which some authors consider very characteristic findings, could not be demonstrated in any of the two patients. The difficulties in the diagnosis of athero-embolic nephropathy and the possible indications of renal biopsy are discussed. Emphasis is made on prevention as the best approach to management, no specific treatment being available.

Aged↗

Hypertension and renal artery aneurysm: spontaneous cure.

An 18-year-old man is described with an aneurysm of the left renal artery diagnosed during study for hypertension. Medical treatment achieved control of the blood pressure. The patient voluntarily interrupted treatment 1 1/2 years after initial diagnosis but the blood pressure remained normal. Angiography at that time revealed almost complete thrombosis of the aneurysm and peripheral plasma renin activity returned to normal in contrast to the high figures registered initially (15 ng. per ml., normal values 0.51 to 2.64). The patient had normal blood pressure, received no medication and was on only a salt-free diet 1 year after this event.

Adolescent↗

Rhabdomyolysis, oedema and arterial hypertension: different syndromes related to topical use of 9-alpha-fluoroprednisolone.

Over a one year period we detected five cases of iatrogenic mineralocorticoidism secondary to topical application of creams containing 9-alpha-fluoro-prednisolone. Although the same product was involved in all cases, the clinical features differed and included two cases of myopathy and hypokalemic rhabdomyolysis, one of oedema and two of arterial hypertension. Discontinuation of treatment and administration of potassium supplements produced a rapid recovery and all patients remain well six months later.

Adolescent↗

Assessment of right ventricular function during supine bicycle exercise after Mustard's operation.

Right ventricular (RV) performance during supine bicycle exercise was evaluated by gated equilibrium nuclear angiography in 19 clinically well children with d-transposition of the great arteries (d-TGA), 6.4 +/- 2.7 years after Mustard's operation. Comparisons were made between rest and peak exercise. The mean resting ejection fraction was 44 +/- 12% (range 30-75%) and was unchanged at peak exercise. Eight children had a normal ejection fraction response, whereas 11 children had either no increase or a decrease in ejection fraction. Relative end-diastolic volumes decreased from resting values in all patients who had an abnormal ejection fraction response. Among patients whose ejection fraction increased, the end-diastolic volume increased in three, decreased in four and was unchanged in one at peak exercise. Heart rate increased 84% (range 52-135%) and systolic blood pressure increased 16% (range 0-28%) at peak exercise. There was no correlation between exercise response and age at surgery or interval since surgery. These data indicate that clinically well children after Mustard's procedure may have abnormal right ventricular function under stress, raising concerns about the ability of the right ventricle to function as the systemic ventricle.

Adolescent↗

Retrospective analysis of Silastic implant arthroplasty of the first metatarsophalangeal joint.

The purpose of this study was to evaluate the outcome of implant arthroplasty according to subjective, biomechanic, and radiographic parameters over a long period of time. Implants in 40 feet (27 patients) were analyzed at an average follow-up time of 8.25 years and a mean patient age of 63. The results were consistent with the subjective findings of previous studies that demonstrated that most patients were satisfied with the procedure. Ninety-six percent of the patients in this study confirmed they would undergo the procedure a second time. The radiographic results did not demonstrate a high incidence of implant fracture as previously reported. This review suggests that implants can be effective when used with patients who are carefully selected according to age, activity level, and diagnosis.

Aged↗

Eosinophilic granuloma of the jaws: a report of three cases.

Three cases of eosinophilic granuloma involving two boys and a girl are reported. Osteolytic lesions of the jaws were seen in all three patients. The two boys presented mandibular lesions, while the girl had lesions in both jaws. Patient age at the onset of the disease was 6 and 9 years in the boys and 10 years in the case of the girl. The affected zone was painful to palpation in all cases, with intra- and extraoral swelling and bone bulging that caused slight facial deformity and bleeding of the gums. Biopsies were obtained in all three cases, and the histopathological study confirmed the diagnosis. The clinical course was favorable in all three children.

Age Factors↗

[Hepatic tuberculosis in a patient with diabetic nephropathy. An unusual clinical presentation].

Hepatic tuberculosis is an exceptional form of presentation of extrapulmonary tuberculosis, but in the last years a greater incidence has been found in patients with HIV infection and/or consumptive diseases or immunosuppressive treatment. For this condition, the diagnosis of hepatic tuberculosis in other population groups represents a true clinical challenge because of the scarce specificity of both the clinical and biological manifestations. Despite deferral of the diagnosis, fast improvement is observed in the clinical symptomatology in most cases following initiation of tuberculostatic treatment.

Diabetic Nephropathies↗