Search PubMed⌕ Search

Biomedical subjects

J Bohm

Publications and source records attributed to J Bohm.

At least 19 recordsLinked to original sources
PubMed1992

Serum ferritin in a Greenlandic Inuit hunter population from the Thule district.

Serum (S-) ferritin was analyzed in 67 Greenlandic Inuit hunters from Thule (Qaanaaq), 35 males and 32 females with a median age of 39 years (range 17-77). S-ferritin was higher in males, median 211 micrograms/l (range 30-1040), than in females, median 87 micrograms/l (range 33-794) (p less than 0.01). None of the subjects had S-ferritin less than or equal to 20 micrograms/l (i.e. depleted iron stores); 5 of the 48 subjects less than or equal to 50 years old had S-ferritin 21-40 micrograms/l (i.e. small iron stores). All 19 subjects greater than 50 years old had S-ferritin greater than 40 micrograms/l (i.e. replete iron stores) and 8 showed values greater than 300 micrograms/l (i.e. increased iron stores). S-ferritin levels increased with the percent energy intake from traditional native hunter food (rs = 0.26, p less than 0.05). Inuit had higher S-ferritin than Danish Caucasian subjects. In Inuit of both sexes, S-ferritin displayed a correlation to age (rs = 0.63, p less than 0.0001 in the entire series), indicating gradually increasing S-ferritin levels during lifetime, without the plateaus seen in Caucasians. These findings suggest continued accumulation of iron reserves in elderly Inuit, due to consumption of large quantities of iron rich meat from marine mammals and/or genetic differences in the regulatory mechanisms for body iron stores.

Adolescent↗
PubMed1991

Health Beliefs Model as a template for measurement of intern satisfaction in an ambulatory care clinical training program.

The Health Beliefs Model was originally developed in the 1950s to assess patient behavior toward preventative health strategies, and has evolved into a tool for measuring a variety of health related topics. Interns in an ambulatory care clinical training program were asked to complete a 62 item self-administered questionnaire based on concepts central to a modified Health Beliefs Model for assessment of their satisfaction with their internship program. A logistic regression was undertaken to identify relationships between interns' perceptions toward susceptibility and seriousness of illness, delivery of health care through outpatient clinics, supervisory professional personnel and their overall internship satisfaction rating. The data implies that the modified Health Beliefs Model is of value in predicting intern satisfaction.

Attitude of Health Personnel↗
PubMed1991

[Modified bedside diagnosis in patients at risk for aortocoronary venous bypass surgery].

Early detection of perioperative complications during cardiosurgical operations is of differential diagnostic and differential therapeutic importance. Various risk groups of aortocoronary venous bypass operations have been analysed under different aspects: age, (not significant), implemented bypass rate (aneurysm resection 1.75/p less than 0.01 compared with 2.65-2.9), death rate (= greater than 21 days) 4 to 6.3% (including patients with "bad ventricle", p less than 0.05), and the proportion of clinically relevant complications of 19 to 40% (aneurysm resection 40%/p less than 0.001). Monitoring the marker proteins is an appropriate method of judging the perioperative risk of perioperative myocardial damage in preoperatively defined high-risk patients (approximately 25% modified according to centre conditions). Patients who died always had early pathologic dynamics of marker proteins. Patients with perioperative risks (aneurysm resection and ejection fraction global less than = 30%), left main artery stenosis and unstable angina pectoris symptoms) were found to have pathologic dynamics of marker proteins to a significantly varying extent (compared to a test group). This modified approach of bedside diagnostics of risk patients confirms the preoperative selection of risk patients and forms the economically viable future basis for an individualized perioperative course control.

Alanine Transaminase↗
PubMed1991

Health care quality assurance: tracer analysis in quality assessment of ambulatory care provided by two out patient teaching clinics.

Population-based assessment of medical care provides information on the quality of care generated by a health care facility over a range of services. Patient chart review was undertaken via "tracer analysis" at two ambulatory care teaching clinics to obtain a measure of the clinical services provided by chiropractic interns for a range of diagnoses. The assessment indicated that chiropractic interns perform best when rendering care for spinal conditions. However, a greater emphasis on development of clinical problem-solving skills versus the use of routine standardized examination procedures would improve the quality of care across a broader spectrum of conditions encountered within the patient base of the clinics. Improved documentation of concurrent medical care or medical referral is warranted in instances of systemic comorbidity.

Ambulatory Care↗
PubMed1990

[Perioperative complications in at-risk patients undergoing heart valve surgery].

The success of operations of the replacement of heart valves is disturbed by perioperative complications and early lethality. A valuation of the perioperative risk individually of patients with operations of the replacement of heart valves according to defined subgroups is controlled by the perioperative course. In order to achieve the registration of patients with perioperative lesion of the myocardium and/or low output syndrome, the bedside performance of a marker protein monitoring consisting of enzymes/isoenzymes (CK, CK-MB, ALAT) and the muscle protein myoglobin, respectively, is necessary. In 38% of the patients with operation of the replacement of heart valves the preoperative risk constellation was objectified early-postoperatively with the proof of complication and thus the strategy of the preoperative individual valuation of the risk confirmed. Altogether patients with replacement of the aortic valve showed the smallest rate of perioperative complications in comparison to patients with replacement of the mitral valve (re-operation in replacement of the mitral valve, double valve replacement, replacement of the mitral valve with restricted left-ventricular function).

Bioprosthesis↗
PubMed1990

Occupational repetitive motion injury: clinical overview and chiropractic implication.

Repetitive motion injury of occupational etiology provides chiropractic an opportunity to expand its clinical use to both industry as well as its patients. An overview of repetitive motion injury is presented including workplace epidemiology, pathophysiology and risk factor assessment. A coordinated plan of action aimed at reducing repetitive motion injury incidence through engineering controls, patient education and clinical therapeutics is offered.

Chiropractic↗
PubMed1989

A serious outbreak of canine distemper among sled-dogs in northern Greenland.

A canine distemper outbreak in a highly susceptible sled dog population of Northern Greenland was recognized in the beginning of January 1988. A high morbidity and mortality in all age groups was a characteristic of the epizootic. The actual canine distemper virus infection was identified by isolation of the virus and demonstration of viral antigens by immunofluorescence and also by demonstration of conventional inclusion bodies. Virus specific IgM antibodies were demonstrated in affected dogs. In places where vaccination was carried out too late to be effective, the losses were up to 80 per cent. In a settlement, which was under rabies quarantine four weeks before the distemper outbreak started in other settlements, no cases occurred before or after vaccination. The spread of canine distemper seems connected with a Canadian outbreak and communicated by foxes. Once established the further spread apparently was by travelling dog teams. Suitable future prophylactic measures are discussed.

Animals↗
PubMed1988

[Initial clinical experiences with heart transplantation in East Germany].

An account is given in this paper of first experience from orthotopic heart transplantation. Six of eight patients with transplants have so far survived, with two of these having been in very good general condition for more than a year. All surgical indications were derived from myocardial dilatation. A triple combination of cyclosporine A, prednisone, and azathioprine was used for immunosuppression.

Follow-Up Studies↗
PubMed1988

[Biochemical studies of the assessment of transplant function following clinical heart transplantation--initial experiences].

Average and specific individual courses of the following parameters are reported in this paper, with reference being made to eight of eleven clinical heart transplantations so far performed at the authors' department: lactate, pyruvate, myoglobin, ASAT, ALAT, GGT, CK, CK-MB, LDH, LDH-1, and glycogen phosphorylase. Glycogen phosphorylase was found to deviate most strongly from normal, with the enzyme exhibiting two initial maxima. The enzyme activity in the serum vanished not later than twelve days from transplantation. The curve of myoglobin was largely parallel to that of phosphorylase. Phosphorylase seemed to be of particular suitability for assessment of ischaemic damage in the wake of transplantation. The individual courses seemed to suggest that none of the investigated parameters exhibited sufficiently sensitive correlations with pathomorphological signs of rejection.

Adult↗
PubMed1987

Bilateral atrial myxomas. Surgical correction after echocardiographic diagnosis.

A case is reported of bilateral atrial myxomas diagnosed noninvasively by echocardiography and successfully removed. The excised tumor mass consisted of a mobile right atrial myxoma prolapsing into the right ventricle and a less mobile, not prolapsing myxoma in the left atrium. The operation was performed entirely on the basis of echocardiographic findings, which correlated well with the operative results. Further investigation by computer tomography verified the diagnosis, but added no extra information of importance for therapy. Diagnostic aspects of the combined application of M-mode and cross-sectional echocardiography with Doppler echocardiography are emphasized. Postoperative follow-up echocardiography showed the complete removal of the myxomas and improvement of cardiac function.

Echocardiography↗
PubMed1986

[Allogeneic heart-lung transplantation--present state and perspectives].

The paper gives a survey of indication, technique, immunosuppression as well as results of the isolated heart transplantation. The isolated heart transplantation represents a genuine therapeutic alternative for many hopeless patients with heart disease who cannot be helped neither with medicamentous nor with the usual cardiosurgical methods. In future the combined heart-lung transplantation might be an essential enlargement of the treatment of patients with terminal heart diseases and with a pulmonary hypertension or of patients with a terminal pulmonary disease.

Cardiomyopathies↗
PubMed1986

[2d operations in coronary artery surgery].

In coronary heart surgery, reoperations are performed on about seven per cent of all cases, primarily for progressive coronary artery sclerosis and sclerosis in autologous bypass veins. The problems relating to progressive coronary artery sclerosis and bypass sclerosis are expounded in this paper by the example of 14 patients, with reference being made to indications for recurrent surgical intervention for vascular reconstruction. Particular emphasis is laid on the surgical approach. With the given risk tolerable, coronary reoperation, today, is a genuine alternative in the treatment of recurrent angina pectoris, following bypass surgery. It is likely to enhance the patient's life expectancy and quality of life.

Adult↗
PubMed1985

[Heart valve replacement with myocardial revascularization].

Coexisting coronary artery insufficiency includes risks to patients with valvular heart disease, thus complicating management. In 15 patients requiring aortic or mitral valve replacement preoperative coronary angiography demonstrated severe coronary stenoses which were treated by bypass grafts with valve surgery. These combined operations turned out to be safe and effective.

Adult↗
PubMed1978

[Coronary heart disease; surgical aspects (author's transl)].

Aspects of indication, of the surgical technique as well as long-term results are discussed on the basis of own experiences in 279 coronary artery operations. Patients suffering from unstable angina pectoris should be operated on as soon as possible. In cases with stable angina pectoris due to a triple vessel disease the long-term results are better with surgery than without.

Angina Pectoris↗
PubMed1978

[Experimental studies on surgical therapy of acute infarct].

The authors examined the effects of reperfusion after temporary ischemia in 50 dogs. The morphologic alterations were documented by methods of electron microscopy, fluorescence microscopy, and histochemistry. Lactate and activity of glycogen phosphorylase were assessed. According to the results, the optimal ischemia interval is 30 to 60 minutes for rational application of reperfusion, while it is just possible after 120 minutes. After a 4-hours-period of ischemia reperfusion increase morphologic damage of myocardium and impairment of myocardial metabolism. Prolonged reperfusion of 7 days resulted in a reduced extent of infarction compared with controls. In non-ischemic myocardium the morphologic and metabolic alterations were less expressed. The effects of "no-reflow"-phenomenon and conclusions for clinical practice are discussed.

Animals↗
PubMed1978

[Reperfusion of the myocardium after acute ischemic lesion].

In a complex experimental study on 52 dogs the myocardium was examined after ischemia and reperfusion of various duration. Morphologic, metabolic, and functional findings proved that a short-term reperfusion after coronary occlusion for more than 2 hours has disadvantageous effects on the regression of ischemic lesions. During the early period (up to 3 days) this is caused by the "no-reflow" phenomenon. Combined qualitative and quantitative findings are required for correct appraisal of the ultrastructural alterations after reperfusion. In acute coronary occlusion, early revascularization after passing the crucial initial phase is advantageous, because the extent of myocardia necrosis is decreased by the prolonged reperfusion, thus leaving a larger myocardiac reserve in case of re-infarction. Clinical conclusions are drawn.

Animals↗
PubMed1976

[Enzyme-histochemical findings in the reperfused heart muscle of the dog (author's transl)].

Enzyme-histochemical changes due to temporary ischemia of canin heart muscle with subsequent reperfusion of the ischemic damaged muscle are described. In relation to findings in the rat, the first enzyme-histochemical changes were observed after two hours of coronary artery ligation. These changes were more impressive after 4 hours of ligation. A further increase was caused by the reperfusion.

Animals↗