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Biomedical subjects

J Bisquert

Publications and source records attributed to J Bisquert.

At least 19 recordsLinked to original sources
PubMed2005

Simple model for ac ionic conduction in solids.

We present a model for the ac conduction in ionically conducting solids that takes into account, in a simple way, the interaction between carriers. The Coulomb force forms an "ionic atmosphere" that exerts a restoring force on a central ion, whose motion corresponds to an overdamped oscillator. We consider the effect of the relaxation of the ionic atmosphere by introducing an additional equation for the displacement of the potential toward the particle position. The general behavior of the ac conductivity can be understood in terms of two types of motions: motion of the bound ion at high frequencies determined by microscopic friction, and a much slower motion coupled to the surrounding carriers relaxation at low frequencies.

Journal Article↗
PubMed2002

[Incidence and risk factors for hepatitis A in the province of Guadalajara (Spain)].

BACKGROUND: The decrease in the prevalence of hepatitis A in Spain may modify the characteristics of this infection because of the rise in the susceptible adult population. The aim of this study was to determine the incidence of this disease, as well as the epidemiological characteristics and the complications of patients diagnosed in the province of Guadalajara between 1991 and 1999. PATIENTS AND METHODS: The inclusion criterion was the presence of specific IgM together with an increase in alanine aminotransferase concentrations and/or symptoms compatible with acute hepatitis. RESULTS: The mean incidence was 7.13 cases/105 inhabitants. Considerable differences were found between years due to the presence of an outbreak. Most cases occurred in children and young adults. The most frequent risk factor found overall was contact with an infected individual but the distribution of risk factors differed between children and adults. CONCLUSIONS: The decrease in the prevalence of hepatitis A in Spain entails an increase in the susceptible adult population. Consequently, hepatitis A may cease to be a typically pediatric disease and may become one that also affects young adults in whom it may have different characteristics. This consideration should be borne in mind when designing a vaccination strategy.

Adolescent↗
PubMed2001

[The prevalence of hepatitis A in the Guadalajara province. Is Spain a country with low endemia?].

BACKGROUND: Spain, together with the other southern European countries, was considered to be an area with a moderate degree of endemia. This fact has consequences for tourists that visit these areas and for vaccination strategies. A prevalence study was proposed in order to get to know the situation of this infection in the Guadalajara province. METHODS: 284 specimens of serum were taken from patients who were classified according to their age, sex and place of residence (with more or less than 10.000 inhabitants). In these specimens the presence of hepatitis A antibodies were studied, using a Microparticule Enzyme Immunoassay (MEIA) (Abbott). RESULTS: An increase in the prevalence was observed in older people, there is a low prevalence population (</= 5%) in people aged between 0-29 years and a high prevalence population (>80%) in adults aged between 30 and 74 years. No differences were observed related to sex. In the stratified analysis according to age, differences were observed between the groups from rural and urban origins. CONCLUSIONS: The low prevalence of hepatitis A was found among the younger population, as seen in other studies carried out on a national level, and this together with a decrease in the frequency, means that Spain is included among the countries with low endemia. This fact has consequences for tourists who visit our country and for vaccination strategies, due to the increase in the number of adults who are susceptible to the infection.

Adolescent↗
PubMed2000

[Urinary infection caused by non typhi Salmonella].

BACKGROUND: The aim of this study was to know the frequency and the clinical characteristics of urinary infection by non typhi Salmonella in our area in Spain. PATIENTS AND METHODS: The clinical histories of patients with urinary infection by non typhi Salmonella diagnosed in the Hospital General del Guadalajara from January 1990 to July 1999 were reviewed. RESULTS: During the period studied nine patients with urinary infection by non typhi Salmonella were diagnosed, representing 0.056% of the urinary infection diagnosed in our hospital over the same period. All the patients presented underlying disease and five were undergoing immunosuppressor treatment. Four patients presented urological disease. The most frequent serogroup was Salmonella enteritidis (7 cases). All the episodes were symptomatic. The same microorganism was isolated in stools in four patients. The evolution was favorable in five of the nine cases. Recurrence was observed in two patients and secondary bacteremia in one. Six patients required antibiotic treatment over two or more weeks. The mean length of treatment was of 2.5 weeks. CONCLUSIONS: Urinary infection by non typhi Salmonella is predominantly observed in patients undergoing immunosuppression or with urological disease. Prolonged antibiotic treatment is recommended due to its bad evolution.

Adolescent↗
PubMed1998

Human infection with Hymenolepis diminuta: case report from Spain.

We report a case of Hymenolepis diminuta infection in a human. The patient was a 5-year-old girl referred to us through the onset of a cyanotic attack. Treatment with a single dose (10 mg/kg of body weight) of praziquantel was ineffective, but the parasite was eradicated after three treatment cycles with the same drug at dosages of 25 mg/kg/day for 5 days.

Animals↗
PubMed1994

[Microbiologic diagnosis of typhoid fever: report on an outbreak].

BACKGROUND: The incidence of typhoid fever has greatly fallen in Spain although sporadic cases and limited outbreaks may be observed. The usefulness of the serum agglutinin studies for the diagnosis of this disease has been questioned by many authors. However, this diagnosis criteria continues to be used in Spain. The usefulness of blood cultures, stool cultures, urinecultures and serological test is herewith compared. METHODS: Three groups were prospectively studied: 18 patients with typhoid fever from one single outbreak, 50 blood donors, and 24 patients with other infections. Blood, stool culture, urinecultures and serology (agglutination) were carried out in the first group and in the other two groups serological test were used to determine the cut-off points and study cross reactions. RESULTS: Blood culture was found to be the most sensitive technique (94%) followed by stool culture (53%). No positive urineculture of seroconvesrion were observed. The cut off points accepted following the study of the donors were 1/160 or greater for the O antigen and 1/320 or greater for the H antigen. Two false positive for the O antigen and 3 for the H antigen were observed in the 24 patients with other infections. CONCLUSIONS: When suspecting typhoid fever, the combined use of blood culture and stool culture is recommended. The usefulness of serological test in our area lays in the observation of seroconversion associated to a compatible clinical picture. Its performance should not being considered as adequate in unspecific febrile syndromes.

Adolescent↗
PubMed1992

Spleen abscess caused by Eikenella corrodens.

A case is reported of splenic abscess due to Eikenella corrodens, a gram-negative rod which is found as part of normal flora in human mucous surfaces. A 64-year-old man presented with fever, chills, anorexia and abdominal pain. Abdominal ultrasound examination showed a perisplenic fluid collection which was considered to be either blood or a subcapsular spleen abscess. The presence of a splenic abscess was later confirmed during surgery and a splenectomy was performed. Splenic purulent material and blood cultures yielded Eikenella corrodens. The patient received cefotaxime for 19 days and was discharged asymptomatic.

Abscess↗
PubMed1991

[Evaluation of 5 selection criteria for sputum as a valid sample for culture].

We compare five selection criteria to discriminate between good quality expectorated sputum and specimens contaminated with upper respiratory tract secretions. We employed two microscopic methods (Bartlett, Heineman) which rely upon the number of squamo-epithelial cells and polymorphonuclear leucocytes; and a macroscopic method (the Medical Research Council) which evaluates the gross appearance of sputum, with three different criteria for admission established by our own. Three hundred and thirty two sputum were included. We evaluated sensitivity, specificity and predictive values as compared with isolation or not of a potential pathogen. We obtained 72% and 45% sensitivity, and 81% and 86% specificity for Bartlett and Heineman methods respectively. Most restrictive criterion for macroscopic method provided 57% sensitivity and 82% specificity; least restrictive showed 97% sensitivity and 17% specificity. Macroscopic method is a quick, valuable screening for discarding sputum contaminated with upper respiratory tract secretions.

Bacteria↗