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Biomedical subjects

J Billet

Publications and source records attributed to J Billet.

At least 19 recordsLinked to original sources
PubMed1995

Effects of carbon monoxide and hypoxia on cleft lip in A/J mice.

Epidemiologic evidence indicates an increase in cleft lip with or without cleft palate [CL(P)] in infants of mothers who smoke cigarettes. It appears that the principle mechanism is through carbon monoxide (CO) decreasing the oxygen (O2) available to the embryo. Previous studies have shown that maternal respiratory hypoxia can increase the incidence of CL(P) in mice. The present investigation was designed to analyze the effects of altered levels of CO and O2 in respiratory gases on the incidence of CL(P) in genetically susceptible A/J mice. Results from blood gas analysis, after a 24-hour exposure of pregnant mice during the time of primary palate development, showed that CO levels of 180 ppm in air decrease oxyhemoglobin (%O2Hb) and increased carboxyhemoglobin (%COHb) to slightly above the high end of the range found in human studies of cigarette smokers. Interestingly, the control COHb levels were higher in our CL(P) sensitive mouse strain compared with those of the range of increases found in human smokers, versus nonsmoker studies, and that the increase for treated mice (3x) was at the low end of the range for smokers. Decreasing O2 levels to 10% from 21% (normal percentage in air) more severely decreased %O2Hb and moderately decreased %COHb. At 24 hours of exposure, the incidence of CL(P) and resorption was approximately the same for both the CO and the control groups, but there were significant increases in the incidence of resorptions in the hypoxia group and of CL(P) in relation to the CO group.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1994

[Treatment of salivary incontinence. A proposal of a new surgical technic and the preliminary results].

Drooling is not induced by an excess of salivary but by incontinence, in case of patients with cerebral palsy and neurologically damaged. Than radical techniques of excision, duct ligations of salivary glands, the authors propose an original association of deviation of submandibular and parotid ducts behind the anterior pillar of soft palate. They discuss it with other therapeutics already proposed in the literature.

Adult↗
PubMed1992

[Biopsy of the salivary glands. The importance and technic of biopsy of the sublingual gland on its anterio-lateral side].

A new method of taking a sublingual gland sample is suggested by the authors in the fore pole. They emphasize on this straightforward operating act and on the amount of tissue removed. The aim of the removal could be etiologic within the framework of the Gougerot-Sjögren's syndrome, diagnostic in the sarcoidosis and rheumatoid arthritis, prognostic in the graft versus host disease.

Biopsy↗
PubMed1990

[Prognostic and therapeutic aspects of lympho-epithelial lesions of the parotid. Apropos of 8 cases].

The so-called benign lympho-epithelial lesion (BLEL) of the parotid is a rare condition. Its diagnosis is based on histology. For a long time there have been problems with its classification and prognosis: classification since certain cases may be classified as Sjögren's syndrome or as a precursor of the latter, prognosis there may be recurrence, contralateral involvement or progression to non-hodgkin's lymphoma. The authors discuss these factors in 8 cases and propose total parotidectomy with facial nerve preservation as the treatment of choice.

Adult↗
PubMed1989

The role of dental canal fillings in the development of Aspergillus sinusitis. A report of 85 cases.

Radiopaque concretions in the maxillary sinus in cases of sinusitis are often observed in infections with aspergillosis. For several authors, such features are considered to be typical of these infections. For us this foreign body in most cases is believed to be related to overfilling of the teeth. We have previously drawn attention to this fact. We report 85 cases of aspergillosis of the maxillary sinus. Cases involving immunosuppressed patients were excluded because of very different clinical conditions. A radiopaque foreign body was seen in 94% of the cases. Of this group, 85% were believed to be related to overfilling of maxillary teeth with dental paste, particularly since evidence for endodontic treatment was found in the premolar/molar region. An image of intrasinus dental paste was demonstrated in 12% of the cases as a direct extension of filling paste from affected teeth. The nature of the dental paste is important because the zinc contained can stimulate the growth of Aspergillus fumigatus. In vitro studies in our laboratory also showed that the growth of A. fumigatus was stimulated with a low concentration of zinc.

Adolescent↗
PubMed1987

[Limited mandibular osteoradionecrosis. Early conservative surgical treatment].

Nine patients with early phase mandibular osteoradionecrosis received conservative treatment involving closure with mucosal and periosteal graft. Early intervention and the limited nature of the osteoradionecrosis are the two fundamental elements for a successful outcome to this conservative therapy, thus avoiding progression to an extensive form requiring interruption mandibulectomy.

Adult↗
PubMed1985

[Angiolymphoid hyperplasia with eosinophilia or Kimura's disease].

A rare affection of unknown etiology that is benign but frequently recurrent, Kimura's disease involves infiltration of the dermis and hypodermis usually of the face. Documented data exists describing clinical findings and results of histopathology that are analogous but are grouped under other names: angiolymphoid hyperplasia with eosinophilia, pyogenic pseudogranuloma, atypical pyogenic granuloma. A case followed up for 13 years is reported.

Angiolymphoid Hyperplasia with Eosinophilia↗
PubMed1984

[The mineral phase of Malherbe's calcifying tumor].

The mineral phase of a calcified tumour of Malherbe (pilomatrixoma) was studied using microradiography, chemical analysis and X-ray diffraction. It was compared with the mineral phase of a piece of human mandibular bone from a matched subject with respect to age and sex. The main part of the mineral phase of the pilomatrixoma belonged to the biological apatite system; an additional whitlockite phase was found. In the homogeneous areas of the tumour, the radioopacity was similar to that of bone.

Calcium↗
PubMed1980

[Conservative surgical treatment for keratocysts of basal cell naevomatosis. Some results (author's transl)].

Excision of keratocysts of basal cell nevomatosis using the principle of conservative surgical treatment of maxillary cysts is usually followed by good secondary bone reconstruction without recurrence. Certain precautions are however necessary, the most important being the resection of the parts of the gums adherent to the cyst wall (where perhaps the cyst developed and where recurrences are most likely to occur). Any tooth germ which may be attached to the cyst must also be removed. Postoperative follow-up must include supervision of the bone reconstruction and tooth germ which have not yet developed (even in the absence of an image of a cyst) until the end of adolescence. In adult age, however, there is very little risk of new keratocysts cysts developing.

Adolescent↗
PubMed1980

[Conservative surgical treatment for large maxillary cysts. Some comments on technique (author's transl)].

Conservative surgical treatment for large maxillary cysts consists of releasing the cystic wall of the bony cavity without destroying the pulp of the teeth which have apices close to the operated cavity (unless the tooth is already dead). The vestibular approach is through one or two orifices and is as small in size as possible. This technique generally allows conservation of the vitality of the largest number of teeth and avoids postoperative collapse.

Bone Cysts↗
PubMed1979

[Micrographic aspect of mandibular osteoradionecrosis (author's transl)].

Fragments of the lower jaw from 42 patients with carcinoma of the oral cavity or oropharynx, and treated primarely with fraction radiotherapy, were excised for radiation osteonecrosis 6 month to 10 years after irradiations. The excised specimens are X-rayed before being coated with methylmetacrylate. They are then cut into thick sections along lines detailled on the X-ray films. The sections are trimmed to 80 microns and examined microradiographically. Two observations are sufficient to demonstrate destruction or reorganisation of the bone tissue. Reabsorption of unusual appearance is seen around the Haversian canals. The newly formed tissue resembles either embryonic bone matter, or lamellar tissue as seen in osteomyelitis.

Aged↗
PubMed1979

[Bone reconstruction after resection of the mandible for osteoradionecrosis (author's transl)].

Resection of the sections of the mandibular affected by osteoradionecrosis has completely modified the progression and prognosis of this affection by ensuring that the patient does not have to suffer long periods of pain and suppuration, constantly observed when medical treatment is used alone. Unfortunately, these resections are usually extensive and are themselves responsible for functional and esthetic sequelae supported with difficulty by some patients, especially in the case of bilateral or mandibular arch resections. All efforts must be made, therefore, to limit the consequences, and with this in mind it is possible: -- to perform an uninterrupted resection limited to the alveolar area involved, in early cases of mandibular osteoradionecrosis; -- to reconstitute mandibular continuity with a bone graft in more advanced stages; -- to improve the esthetic appearance with skin and subcutaneous grafts whenever this is necessary. Good results can only be obtained if certain anatomical conditions exist and if surgical precautions are adapted to each case.

Adult↗