This paper describes the autoradiographic distribution of VIP binding sites in the rat central nervous system using monoiodinated 125I-labeled VIP. High densities of VIP binding sites are observed in the granular layer of the dorsal dentate gyrus of the hippocampus, the basolateral amygdaloid nucleus, the dorsolateral and median geniculate nuclei of the thalamus as well as in the ventral part of the hypothalamic dorsomedial nucleus.

Animals↗

PubMedDate not supplied

[Vip in human neonates and infants. As measured by radioimmunoassay and radioreceptorassay (author's transl)].

The Vasoactive Intestinal Peptide (VIP) was assayed in the gut of human neonates and premature infants immediately after death or surgery. In these conditions, values ranged between 150 and 740 ng/g of bioled tissue. The implication of VIP in Vermer-Morrison syndrome is further assessed by the correlation between clinical symptomatology and plasma VIP levels. The immunoassayable VIP (IA-VIP) extracted from normal gut or tumor is shown to fully interact with specific receptor for VIP in liver. This fact suggests the biological potency of IA-VIP.

Biological Assay↗

PubMedDate not supplied

Lamellar keratoplasty with the Barraquer microkeratome.

Lamellar keratoplasty was performed in 17 eyes: 6 with corneal opacities following epidemic keratoconjunctivitis, 3 with herpes keratitis, 2 with anterior corneal dystrophies, and 6 others. The Barraquer microkeratome was used for the resection in both the host and the donor. A technique is described to correct major disparities in diameter between the bed and the donor disc. In eyes with vision limited only by corneal diseases (11), the best postoperative spectacle corrected visual acuity was 20/25; the mean postoperative spectacle corrected visual acuity for the 11 eyes was 20/40.

Adolescent↗

PubMedDate not supplied

[Study in man of butobarbital pharmacokinetics, under polygraphic monitoring].

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Adult↗

PubMedDate not supplied

[Histological and immunological aspects of allergic and non allergic nasal mucosae. A study of 64 biopsies (author's transl)].

Optical and immunofluorescent microscopy was used to examine 52 pathological nasal mucosae (41 allergic, 11 non-allergic), and the results were compared to the clinical, biological and allergic findings. It was noted that there were a large variety of histological lesions in each group of patients, their extent being related much more to the duration and severity of the aggression than to their nature. There appears to be a relation between the extent of the anatomical lesions and immunological activity, non-allergic mucosae being low in immunoglobulin levels.

Adult↗

PubMedDate not supplied