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Biomedical subjects

J Berth-Jones

Publications and source records attributed to J Berth-Jones.

103 records · Page 6Linked to original sources
PubMed1989

Failure of terfenadine in relieving the pruritus of atopic dermatitis.

We report the results of a double-blind, placebo-controlled, cross-over study of terfenadine 120 mg twice daily for pruritus in atopic dermatitis. Twenty-eight subjects with chronic atopic dermatitis received both terfenadine 120 mg b.d. and placebo each for a period of 1 week. Response was recorded by the subjects using visual analogue scales for severity of pruritus twice daily for the last 4 days of each treatment phase. There was no benefit from terfenadine.

Adolescent↗
PubMed1989

Carcinoma-associated dermatomyositis responding to plasmapheresis.

We report a case of severe carcinoma-associated dermatomyositis which, having shown no response to conventional treatment, improved markedly within 48 h of plasmapheresis. We believe that this is the first time that dermatomyositis associated with an advanced carcinoma has been reported to respond in this way. Dermatomyositis can prove extremely difficult to treat and sometimes fails to respond even to very high doses of steroids and immunosuppressants. There is currently only a single report of the use of plasmapheresis in adult dermatomyositis. We therefore wish to support the findings of Dau and draw attention to the value of this therapeutic option in refractory dermatomyositis.

Adenocarcinoma↗
PubMed1989

A family with palmoplantar epidermolytic hyperkeratosis.

Familial epidermolytic hyperkeratosis confined to the palms and soles was first characterized by Klaus and Weinstein in 1970. This entity has been the subject of only four subsequent reports. We report a family previously diagnosed as suffering from tylosis (Thost Unna syndrome), in which eleven members have been affected, and review the literature on this disease. It would seem possible that this entity may be more common than the sparse literature would indicate, and that other cases may currently be masquerading as tylosis.

Adolescent↗
PubMed1989

Juvenile spring eruption of the ears.

We report two patients with a distinctive bullous photodermatosis conforming to the previously described entity, 'juvenile spring eruption of the ears'. This is an unusual bullous photodermatosis, which develops over the light exposed areas of the ears, usually in the spring. Boys and young male adults are most commonly affected. Juvenile spring eruption receives scant attention in dermatological texts, and to our knowledge no cases have been reported in the English literature since 1954.

Child↗
PubMed1989

Lichen sclerosus.

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Adolescent↗