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Biomedical subjects

J Bernard

Publications and source records attributed to J Bernard.

At least 433 records · Page 24Linked to original sources

Treatment of acute myeloblastic leukaemia with RP 22050.

Fourty-four patients with acute myeloblastic leukaemia were treated with RP 22050, a new, semisynthetic derivative of daunorubicin. Complete remissions were achieved in 20 patients (45%). The median dose given was 23 mg/kg. The toxicity of RP 22050 is mainly haematological. Resistance rather than death in aplasia seemed to be the cause of failure of therapy.

Adult↗