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J Bermejo

Publications and source records attributed to J Bermejo.

At least 73 records · Page 4Linked to original sources
PubMed1992

[Orthotopic liver transplantation in the Budd-Chiari syndrome. A case report].

A patient with Budd-Chiari's syndrome of idiopathic etiology, received an emergency liver transplant because of terminal liver insufficiency, including encephalopathy, functional renal failure and progressive deterioration of coagulation. The diagnosis was confirmed by biopsy. The transplanted liver was from a patient with the same blood group and the preserving solution was Euro Collins. No veno-venous by-pass was necessary during operation. Anticoagulation was started from the immediate post-operative stage, as well as triple immunosuppressive therapy with azathioprine, cyclosporine and corticoids. The patient is asymptomatic twenty months after transplantation.

Adult↗
PubMed1991

[Barrett's esophagus does not revert after medical or surgical therapy for gastroesophageal reflux].

An evaluation was made of 34 patients having Barrett's oesophagus. Medical therapy consisted of antacids, H2 blockers, orthopramides, and postural measures (20 cases, mean follow-up 2.9 years). A Nissen fundoplication was done in 14 cases (mean follow-up 2.5 years). Clinical, endoscopic and histologic evaluation was done in all patients and pH measurements also done in all operated cases. Clinical results have been excellent in 70% of medically treated patients and in 100% of surgically treated ones, pH measurements were between normal limits in all operated patients. However, recovery of the normal epithelium did not occur in any case, except for some partial improvement in one patient treated surgically.

Adolescent↗
PubMed1988

Effect on growth of children with cardiac dysrhythmias treated with amiodarone.

We report the results of treatment with amiodarone in nine children with dysrhythmias resistant to conventional drugs, namely, one with ventricular tachycardia, two with atrial tachycardia, one with junctional tachycardia, three with reciprocal rhythm tachycardia, and two with Wolff-Parkinson-White syndrome. The initial dose was 800 mg/1.73 m2, administered for two weeks, followed by half the dose for five days a week. The duration of the treatment varied from nine months to 19 months (mean duration, 13 months). Patients were followed up for a period ranging between nine and 33 months (mean period, 17 months). A complete remission was obtained in 56% of patients and partial success in 46%. The following side effects were detected: photosensitization in two; effect on weight, height, growth velocity, and thyroid hormones in three, six, five, and six, respectively; and acceleration in bone age in three. These effects were observed from two to nine months after the beginning of treatment. They persisted for 5-18 months after treatment had been suspended. The main side effect of amiodarone in children is presumably initial hypothyroidism, followed by a biological hyperthyroid reaction. For these reasons we suggest that amiodarone should be restricted as an alternative drug for resistant critical dysrhythmias and be used only for a limited period of two years.

Adolescent↗
PubMed1987

[Amiodarone in children. Impact on growth].

In this work, we report the results of the treatment with amiodarone applied to 9 children suffering from dysrhythmia resistant to conventional drugs. The initial dose was 800 mg/1,73 m2, administered for two weeks, followed by a 50% dose administered 5 days a week. The duration of the treatment oscillated from 9 months to 15 months (average duration: 13 months). Patients were kept under control for a period ranging between 9 and 33 months (average period: 17 months). A complete remission was obtained in 56% of the cases and partial success in 46%. The following side effects were detected: photosensitization in 2 cases; repercussion on weight, height, growth velocity, thyroid hormones and acceleration in skeletal age in 44% and 66% of them. These effects could be observed from 2 to 8 months after the beginning of the treatment. They persisted for 5 to 18 months after the treatment was arrested. The main side effect of amiodarone in children is presumably an initial effect of hypothyroidism, followed by a biological hyperthyroidism reaction. For these reasons we suggest that amiodarone should be restricted as an alternative product for resistant critical dysrhythmias and be used for a limited period of two years only.

Amiodarone↗
PubMed1985

NH resonances of Ribonuclease S-peptide in aqueous solution. Low temperature n.m.r. study.

A detailed study of the NH resonances of Ribonuclease-S-peptide (1-19 N-terminal fragment of Ribonuclease A) has been carried out in H2O, pH 3.0, in the temperature range 1-31 degrees, and ionic strength 0-1 M. Individual assignments of all NH amide signals have been achieved by means of extensive double resonance experiments. The folding of S-peptide at low temperature has been monitored by examination of the several NH resonance parameters: first, the nonlinearity of chemical shift vs. temperature plots; second, the selective broadening observed for signals assigned to residues 3-13; and third, the decrease of 3JHNCH coupling constants belonging to this region of the polypeptide chain. All these results are in agreement with the formation of a folded structure at low temperature, which is similar to the one found for the S-peptide in the RNase S crystal.

Amides↗
PubMed1983

[Ventricular tachycardia in a healthy child. Electrophysiological study and review of the literature].

Report of a healthy child with ventricular tachycardia is the reason for a review on the literature on this subject. Diagnosis can be made with usual electrocardiographic criteria and surely by electrophysiologic studies. Latter technique allows to study the origin, mechanism, efficiency of drugs and the type of pace-maker in case of drug treatment failure. Case report exemplifies all these aspects, and the essentials about etiology, symptoms, diagnosis and treatment are mentioned in the literature review.

Anti-Arrhythmia Agents↗
PubMedDate not supplied

HLA-DRB1 and -DQB1 polymorphism in liver recipients: relationship between HLA-DQB1*0302 allele frequency and acute rejection.

Polymorphism of HLA-DRB1 and HLA-DQB1 loci was performed in fifty-three orthotopic liver graft recipients as well as in 108 unrelated healthy controls. Nonradioactive SSOPs were used to study PCR-amplified DNA from peripheral blood lymphocytes and biopsied material. The comparison frequency for DQB1 alleles did not reveal any significant differences between the total group of liver recipients and controls. However, when the liver recipients were subgrouped according to their rejection episode manifestations, increased and significant frequencies were observed for HLA-DQB1*0302 allele in patients showing acute rejection episodes compared to healthy controls or patients without acute rejection. This relationship did not appear influenced by the amino acid beta alanine residue in the 57th position. On the other hand, the study of the DRB1 allele frequencies did not show significant differences in any study. These results suggest that HLA-DQB1 genes could be important in the liver graft alloresponses, opening a way to a better understanding of the special tolerance state, normally observed in this type of transplant, leading us to consider the possible HLA-DQB1*0302 allele effect on tolerance rupture.

Alleles↗
PubMedDate not supplied

[Ankle infection].

Explore the source record for details and available documents.

Ankle Joint↗