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Biomedical subjects

J Berge

Publications and source records attributed to J Berge.

26 records · Page 2Linked to original sources

Cavernous sinus thrombosis diagnostic approach.

We report three cases of cavernous sinus thrombosis and compare the values of three imaging methods: orbital phlebography, computerized tomography (CT) and magnetic resonance imaging (MRI). On the other hand, we performed 2D "time of flight" MRI flow sequences on a series of subjects with normal cavernous sinus. Visualization of cavernous veins in all subjects by this method makes it possible to consider using it for the diagnosis of undoubtedly cavernous sinus thrombosis in all safety. MRI-angiography, therefore, may replace orbital phlebography.

Adult↗

Novel alpha 2-adrenoceptor antagonists show selectivity for alpha 2A- and alpha 2B-adrenoceptor subtypes.

Pharmacological characterization of mammalian alpha 2-adrenoceptors in various tissues and species has provided evidence for the existence of two alpha 2-adrenoceptor subtypes. These subtypes can be defined in rat and human tissues by prazosin which is alpha 2B selective and oxymetazoline which is alpha 2A selective. In addition to these agents, two types of alpha 2-adrenoceptor antagonists are described which show high affinity and selectivity for the alpha 2A-adrenoceptor and the alpha 2B-adrenoceptor respectively.

Adrenergic alpha-Antagonists↗

Single-mosquito test to determine genotypes with an acetylcholinesterase insensitive to inhibition to propoxur insecticide.

A sensitive technique allowing to identify the three genotypes (AceSS, AceRR and AceRS) of the Ace gene existing in natural populations of Culex pipiens in southern France is described. The technique is based on the comparison of AChE (acetylcholinesterase) activity in 3 equal aliquots taken from the homogenate of a single mosquito (a) in absence of inhibitor (RA), (b) in presence of eserine that inhibits the AChE encoded by AceS and AceR alleles (RI) and (c) in presence of a concentration of propoxur inhibiting the AChE coded by the AceS allele but not by the AceR allele (RG). The mosquito tested is AceSS when RG = RI, AceRR when RG = RA and AceRS when RI less than RG less than RA.

Acetylcholinesterase↗

Age-related changes in the cervical spines of front-line rugby players.

Cervical spine trauma occurs frequently in front-line rugby players. To evaluate the accumulative effects of this trauma, magnetic resonance imaging scans of the cervical spine were performed on 47 rugby players and 40 age-matched control subjects. The aim of this study was to compare the changes in the cervical spine of players at different points in their careers. A study of cervical spine changes, including spinal curve, spinal constituents, posttraumatic deformities, and degenerative modifications, was completed by a study of cervical measurements. Front-line rugby players showed more early degenerative alterations on magnetic resonance imaging scans than did the control subjects of the same age. These changes correlated with age and were probably linked with repetitive cervical trauma throughout the players' careers. Particular attention should be paid to the data confirming cervical spine canal stenosis in front-line players, which may place these athletes at risk for acute neurapraxia while playing this collision sport.

Adult↗