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J Bengtsson

Publications and source records attributed to J Bengtsson.

30 records · Page 2Linked to original sources

Sampled gas need not be returned during low-flow anesthesia.

OBJECTIVE: The purpose of this investigation was to study the N2 flux between the patient and the breathing circuit, and the excess gas during N2O anesthesia with the low, fresh gas flow technique. METHODS: Forty patients were studied. After a 6-minute high, fresh gas flow denitrogenation period, the O2 fresh gas flow was set at about 4 ml/kg/min and the N2O fresh gas flow was set to maintain an inspired O2 fraction of 0.30. The excess gas flow and N2 excretion were measured by a variant of the Douglas bag method. RESULTS: The mean inspired N2 concentration reached a peak of 5.9% at 40 minutes. The estimated mean N2 excretion was 39 ml/min at 10 minutes, declining to 18 ml/min at 60 minutes. A calculation of N2 homeostasis during closed-circuit anesthesia based on the results of the patient study indicated that sampling for gas analysis actually reduces the gas costs if the sampled gas is scavenged instead of returned to the circle system, since intermittent flushing with high, fresh gas flow for denitrogenation is unnecessary in the former situation. CONCLUSIONS: Regardless of the fresh gas flow used, sampled gas need not be returned during N2O anesthesia.

Adult↗

[Respiratory gas exchange. Anesthesia with enflurane or isoflurane in nitrous oxide during spontaneous and controlled ventilation].

The estimation of oxygen consumption and carbon dioxide elimination is essential for predicting the metabolic activity and needs of any patient having anaesthesia. During anaesthesia oxygen consumption can be measured and compared to a predicted value. However, oxygen uptake is affected by anaesthetic agents, which complicates the interpretation of measured oxygen uptake rate. The purpose of this study was to investigate whether there are any differences in respiratory gas exchange during anaesthesia with enflurane and isoflurane and also to assess the effects of spontaneous versus controlled ventilation. METHODS. Forty orthopedic patients were randomized to enflurane or isoflurane anaesthesia in nitrous oxide with either spontaneous or controlled ventilation. A fresh low-gas-flow technique was used. Inspiratory oxygen and end-tidal carbon dioxide concentrations and expiratory minute ventilation were measured in a circle absorber system between the y-piece and the endotracheal tube with a sampling analyser. Between the mixing box and the absorption canister, carbon dioxide concentration was continuously measured. The carbon dioxide elimination was calculated from mixed expired concentration and expiratory minute ventilation. Excess gas was collected every 10 min in a non-permeable mylar plastic bag connected to the excess valve. The excess gas flow was calculated and the oxygen uptake rate was assumed to be the difference between the oxygen fresh gas flow and the oxygen excess gas flow. RESULTS. The grand mean oxygen uptake rate was 2.5 ml.kg-1 x min-1 or 100 ml.min-1 x m-2. There were no statistically significant differences in oxygen uptake between enflurane and isoflurane anaesthesia or between spontaneous and controlled ventilation. The mean oxygen uptake rate at 10 min was between 2.0 and 2.2 ml.kg-1 x min-1 in all groups. At 30 min the mean oxygen uptake rates were 2.6 to 2.8 ml.kg-1 x min-1. Carbon dioxide elimination was closely associated with expired minute ventilation, with a carbon dioxide excretion of about 30 ml per litre gas exhaled, irrespective of ventilatory mode employed.

Adult↗

N-linked glycopeptides with blood group determinants lacking neuraminic acid from the epithelial cells of rat small and large intestine.

The N-linked type of glycans were prepared as their glycopeptides after pronase digestion of the epithelial cells from the small and large intestine of two inbred strains of rat. These glycopeptides were analysed for sugar composition, for blood-group activity, by 1H-NMR spectroscopy, and after permethylation by electron-impact mass spectrometry. The glycopeptides were of the triantennary and tetraantennary types with intersected GlcNAc. The terminal parts were, in contrast to most N-linked glycans, devoid of neuraminic acid residues. Instead they contained blood-group determinants. Blood-group-H types 1 (Fuc alpha 1-2Gal beta 1-3GlcNAc) and 2(Fuc alpha 1-2Gal beta 1-4GlcNAc) were found in the small and large intestines of both strains, although type-1 predominated. One rat strain (GOT-W) did not express blood-group-A glycopeptides in the small intestine, but the large intestine from the same strain did. The other strain (GOT-BW) expressed blood-group-A determinants in the small intestine. The lack of neuraminic acid residues in the small and large intestine and of blood-group-B activity in the large intestine differed from that found in glycosphingolipids obtained from the same organs.

Animals↗

Penile blood pressure.

Measurement of penile blood pressure has been advocated for investigation of erectile impotence due to arterial insufficiency in the penis. Using both strain gauge plethysmography and ultrasonic technique, and expressing the penile blood pressure as an index of the brachial blood pressure, the coefficient of variation in double determinations in non-arteriosclerotic, potent men was 6%. The normal range of the index was 0.7 to 1.02. More than 90% of men with arteriosclerotic disease of the legs and penile blood pressure index below 0.60 were impotent. The penile blood pressure thus can demonstrate, though it does not exclude, arterial insufficiency in the penis.

Adult↗

A descriptive cross-sectional study of annoyance from low frequency noise installations in an urban environment.

In order to improve the living conditions for respondents highly exposed to traffic noise, it has been recommended that one side of the building should face a "quiet side". Quiet may, however, be spoilt by noise from installations such as ventilation and air-conditioning systems. The noises generated by installations of this kind often have a dominant portion of low frequencies (20-200 Hz) and may be a source of great annoyance and sleep disturbance. This paper describes the cross-sectional part of an intended intervention study among residents exposed to traffic noise on one side of the building and to low frequency noise from installations on the other side of the building. A questionnaire masked as a general living environment study was delivered to a randomly selected person in each household. In total 41 respondents answered the questionnaire (71% response rate). Noise from installations was measured indoors in a bedroom facing the courtyard in a selection of apartments and outdoors in the yard. 24h traffic noise outdoor and indoor levels were calculated. The noise levels from installations were slightly above or at the Swedish recommendations for low frequency noise indoors with the window closed and exceeded the recommendations by about 10 dB SPL when the window was slightly opened. The proportion of persons who reported that they were very or extremely annoyed indoors from noise from installations was more than twice as high as for traffic noise. Installation noise also affected respondents' willingness to have their windows open and to sleep with an open window. The high disturbance of installation noises found in this study indicates the importance of also regulating the noise exposure on the "quiet side" of buildings. Further studies will give a better base for the extent of annoyance and acceptable levels of installation noises.

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