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Biomedical subjects

J Baumgartner

Publications and source records attributed to J Baumgartner.

At least 55 records · Page 3Linked to original sources

Embedding trees in the rationals.

An example is presented of a simple algebraic statement whose truth cannot be decided within the framework of ordinary mathematics, i.e., the statement is independent of the usual axiomatizations of set theory. The statement asserts that every tree-like ordering of power equal to or less than the first uncountable cardinal can be embedded homomorphically into the rationals.

Journal Article↗

Use of immunoglobulins in prevention and treatment of infection in critically ill patients: review and critique.

The study of the use of standard intravenous immunoglobulin (IVIG) preparations as adjunctive therapy for seriously ill patients is motivated by the need to restore immunoglobulin G depleted because of trauma or surgery and/or by the need to provide patients with specific antibodies to various microorganisms. Whereas no clinical studies have shown that standard IVIG has therapeutic efficacy, some data suggest that its prophylactic use is beneficial. Antisera or IVIG prepared from individuals who are hyperimmunized with the biologically active, highly conserved core portion of the endotoxin of gram-negative bacteria confer variable degrees of protection in animal models and clinical trials. Two clinical trials with use of monoclonal antibodies to core lipopolysaccharide have been completed. Only subsets of patients with gram-negative sepsis were protected by the monoclonal antibodies, but the results of the studies were discrepant in regard to the specific characteristics of patients who benefited from the administration of these antibodies. Further studies will be necessary to establish whether this therapy can be recommended for critically ill patients.

Antibodies, Monoclonal↗