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Biomedical subjects

J Bartel

Publications and source records attributed to J Bartel.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Fetal echocardiography--possibilities and limits].

Actual possibilities and limitations in fetal echocardiography (two-dimensional and impulse-Doppler technique) based on our own experiences in 53 cases are described. Morphological analysis was almost successful after the 22nd week of gestation, in 11.3% the imaging was inadequate as the result of unfavorable ultrasound viewing. In twins especially the morphological analysis of the second fetus was more difficult. Clear morphological differentiation from the important parts of the fetus heart was possible after the 30th week of gestation in the majority of cases. From 47 sonographically judgeable fetal hearts 3 were classified as malformations. One of them could be confirmed by autopsy (ventricle-septal defect combined with cor monatrium), the second case clinically/echocardiographically postpartally respectively (atrial septal defect - secundum type). On the other hand the third pathological diagnosis of fetal echocardiography (single ventricle) could not be confirmed post-natally. As the result of this preliminary study fetal echocardiography can currently provide some important clues for the selection, perinatological treatment and care in birth of the child with a potentially higher risk factor. Additionally the authors point out the possibilities of complex functional analysis of the fetal heart under different pharmacological treatment.

Diagnosis, Differential↗
PubMed1982

[Erythrocyte creatine concentration in infants and children with congenital heart disease and left-to-right shunts (author's transl)].

The creatine concentration of red blood cells was determined in 58 children with congenital acyanotic malformations of the heart at the age of 3 weeks to 3 1/2 years. It was correlated to the severity of the hemodynamic changes, the physical development of the children and number of reticulocytes. The average creatine concentration in the red cells of all patients was 12.8 +/- 4.80 mg/100 ml cells, i.e. twice as high as that of the control group (6.61 +/- 1.19 mg/100 ml cells). Particularly high creatine values were found in children, who died in consequence of their heart disease without previous operation (18.49 +/- 4.25 mg/100 ml cells, n = 11) and those children who had to be operated on as a life-saving measure (17.88 +/- 3.43 mg/100 ml cells, n = 10). The highest creatine concentration was found in a 4 weeks-old infant with hypoplastic left heart syndrome (25.3 mg/100 ml cells). In children with a systolic pressure in the pulmonary artery of greater than 50 torr the creatine concentration was significantly higher than in those with pressures less than 50 torr. Increased creatine values correlated well with the poor physical development and increased reticulocyte numbers of the children. There was no correlation found between capillary pO2 and creatine concentration. It is concluded that the determination of erythrocyte creatine in children with congenital heart disease of the left-right shunt type furnishes additional objective information on the general condition of the organism and its adaptation capacities to hypoxia. It may serve as a valuable diagnostic and prognostic measure.

Blood Cell Count↗