[Hemorrhagic rectocolitis associated with idiopathic chronic pancreatitis].
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Biomedical subjects
Publications and source records attributed to J Barge.
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The authors report the case of an eighty-three-year-old woman with giant-cell arteritis who experienced recurrence five years after the withdrawal of corticosteroids which had been given for four consecutive years. This recurrence, demonstrated by arterial biopsy, was accompanied with Sjögren disease proven upon histological examination. With reference to this case-report, the various possible courses of protracted giant-cell arteritis are discussed; relapses occurring more than one year after therapy is discontinued are exceptional.
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A case of tropical sprue in a 73-year old parisian male returning from endemic areas is reported. Clinical manifestations were megaloblastic anemia, malabsorption and protein-losing enteropathy. Biopsy of the jejunal mucosa showed partial villous atrophy with thickening of the basement membrane region; fat droplets were observed inside and close to the epithelial cells on electron microscopy study. Fat intestinal absorption after a test meal was delayed. Clinical, biological and histological improvement was obtained with tetracycline and folic acid therapy. The particular clinical and anatomical features of this case, as well as the difficulties for establishing the diagnosis of tropical sprue in non-endemic areas are analyzed.
Hepatic carcinoma revealed by Budd Chiari syndrome in an eighty-four-year-old female patient is reported. With reference to this observation and to the twenty-two other cases previously reported in the medical literature, the specific pathological and clinical features of Budd Chiari syndrome caused by primary carcinoma of the liver are reviewed. Histological features of the liver tumour are discussed.
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The clinicopathological features of 10 cases of superficial oesophageal carcinoma without lymph node metastasis are reported. Superficial oesophageal carcinoma, an uncommon form of oesophageal cancer, is defined as invasive squamous cell carcinoma confined to the mucosa and submucosa. It includes plaque-like, erosive, papillary and occult types but is not associated with the usual macroscopic features of advanced oesophageal cancer. The main presenting symptom of dysphagia and oesophagitis is a frequently quoted endoscopic diagnosis. Superficial oesophageal carcinoma may be preceded by dysplastic and in situ carcinomatous changes and is probable oesophageal counterpart to early gastric cancer.
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A woman of 40 years of age without any past history of urinary affections was discovered to have malacoplakia of one kidney, demonstrated by a mass in the right flank, fever, and a coliform urinary infection. No secretion from the affected side was observed on intravenous urography. Renal arteriography showed an inflammatory mass affecting mainly the lower half of the kidney. Histological examination of a nephrectomy specimen led to a diagnosis of a malacoplakia. The authors review the clinical, radiological, and pathological features of renal malacoplakia, which is an inflammatory condition of the renal parenchyma very similar to xantogranulomatous pyelonephritis. The pathogenesis is completely unknown, but the lesion probably arises from a disorder of macrophage function, and renal malacoplakia should be a differential diagnosis of inflammatory renal masses.
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A search for immunoglobulin deposits in normal and fibrous interstitial tissue was carried out on 100 bone marrow biopsies (44 myeloproliferative disorders and 56 other hemopathies). This preliminary study enabled one to draw three conslusions: 1) The search for immunoglobulins is only possible on non-decalcified bone marrow. The direct immunofluorescent technique gives better results than peroxidase staining: 2) In myeloproliferative disorders immunoglobulins (especially G) are more frequent and more often associated with a myelofibrosis than in other hemopathies, and 3) The more pronounced the fibrosis the more frequent the immunoglobulin deposits, except at the osteomyelosclerosis stage. They are never found in the fibrosis secondary to intramedullary carcinomatous metastases.