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Biomedical subjects

J Bardach

Publications and source records attributed to J Bardach.

At least 73 records · Page 4Linked to original sources

Dysmorphophobia: symptom or disease?

Although dysmorphophobia, a subjective feeling of ugliness in a person of normal appearance, constitutes a distinctive symptom cluster occasionally seen in patients requesting cosmetic surgery, it is not included in current major psychiatric diagnostic systems. Patients with dysmorphophobia are usually young and perfectionistic and have both schizoid and narcissistic traits. The authors present two representative case histories and suggest that study of more patients with dysmorphophobia is needed to determine whether it is a symptom of an underlying disease or is itself a separate disease entity.

Adolescent↗

The influence of primary unilateral cleft lip repair on facila growth.

The lip pressure exerted by the repaired cleft lip was studied in 35 rabbits during a 20-week period. Animals were divided into four groups. Two of them were controls, and in the other two, two different surgical procedures were used for the lip repair. The results of this study indicate that there was reduction in lip pressure resulting from the surgically induced cleft lip, alveolus, and palate. Substantial increases in lip pressure were shown in both groups in which lip repair was completed. The influence of primary unilateral cleft lip repair on the facial growth of rabbits in this study will be presented in Part II of this report.

Animals↗

Reconstruction of the oral cavity with a free flap.

Free groin flaps were used successfully within the oral cavity in 4 patients after ablative operations for cancer. Preoperative or postoperative radiation (cobalt therapy) had no apparent detrimental effect on the survival of these free flaps.

Adult↗

The short arm deletion syndrome of chromosome 4 (4p- syndrome).

Partial deletion of the short arm of chromosome 4 (4p-) represents another (rare) cause of cleft lip and cleft palate. Further characteristic manifestations of the syndrome (also called Wolf or Wolf-Hirschhorn syndrome) are growth failure, microcephaly, prominent glabella, hypertelorism, beaked nose, poorly differentiated and low set ears, cardiac and renal malformation and hypospadias. Life expectancy is often shortened. The 4p- syndrome has many features in common with another deletion syndrome, the cri-du-chat syndrome, and also with the Smith-Lemli-Opitz syndrome. The latter is a hereditary condition with normal karyotype. The cri-du-chat syndrome is characterized by a peculiar high-pitched, mewing cry and can be differentiated from the Wolf syndrome by the different staining characteristics (banding) of chromosomes 4 and 5.

Abnormalities, Multiple↗

[Rhinoschisis].

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Abnormalities, Multiple↗

Fluorescein test in the prediction of viability of skin flaps on pigs.

The fluorescein test is widely used in clinical and experimental studies for prediction of the viability of skin flaps. A thorough search of the literature revealed that the accuracy of this test had never been studied. Therefore, this study was designed to evaluate the accuracy of the fluorescein test in predicting the viability of skin flaps. A total of 212 unipedicle porcine skin flaps were used in this study. Statistical analysis demonstrated that the surviving area of the flap was significant greater than the staining area of the flap. We suggest that caution be exercised when the fluorescein dye test is used to assess skin flap viability and that the test be used for an approximate indication and not for an accurate prediction of the surviving flap area.

Animals↗

The role of photoplethysmography in the prediction of the experimental flap survival.

A standard photoplethysmography, modified to differentiate between arterial and venous vasculature in skin tissue, has been used to measure arterial supply in 100 unipedicle skin flap in 25 pigs. A datum transform from a light intensity scale to a relative arterial blood density scale has been introduced and empirically labeled the vascular coefficient (VC). Statistical analysis of the VC data shows a significant difference between necrotic and surviving flap group mean data as early as 24 hours. Additional analysis in which a normal ogive was fitted to the sample VC data distributions suggests that statistically significant predictions of the probability of eventral flap necrosis can be made using VC measurements obtained immediately postoperatively. It is concluded that the modified photoplethysmograph, in conjunction with the VC data transform constitutes a usable measuring technique for skin flap viability prediction in the experimental animal.

Animals↗

An alternative approach to the pterygopalatine fossa by removing the mandible and immediately replacing it.

A case is presented with a child with a desmoid tumor of the pterygopalatine fossa in which approximately a third of the mandible including the condyle was removed for exposure. The trimmed mandibular segment was then returned to position with a fascia cap over the condyle and intermaxillary fixation was instituted. The graft was followed by serial roentgenogram over five years. The graft took completely, grew with the patient, and resulted in normal dental occlusion and normal mandibular excursion.

Bone Neoplasms↗

Experimental study on the closure of large defects of the oral cavity using a free island flap with microvascular anastomosis.

The present study demonstrates that a free island flap with microvascular anastomosis may be used for the closure of a large defect in the oral cavity of the pig. In control cases, when a similar flap was transferred without microvascular anastomosis, a total and rapid slough occurred. Technical details are important in this kind of surgery. The island flap should be sized appropriately, cautiously defatted, and sutured into the defect before doing the microvascular anastomosis. Tension, torsion, or kinking of the vessels to be anastomosed must be meticulously avoided. In suturing these small vessels, microvascular techniques must be strictly adhered to. No anticoagulation is needed. The free island flap does not need to be perfused. Close observation of the flap's capillary refill, tissue turgor, and color is essential in the early postoperative period. More recently, Doppler technique has enabled us to monitor blood flow in the flap more accurately. If initial signs of venous congestion or arterial insufficiency are noted, examination of the anastomotic site can and should be done. Revision, if indicated, may result in rescue of the flap (as it was described in pig No. 8). The results of this experimental study allowed us recently to use this method successfully in two patients. Both had oral cavity carcinomas. In the first, the flap measured 5x7x2 cm and in the second 9x10x1.5 cm. They are now nine weeks and five weeks respectively, without any signs of failure. The details will be given when we have a series of patients adequate for a definitive report.

Abdominal Muscles↗