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Biomedical subjects

J Barbour

Publications and source records attributed to J Barbour.

18 recordsLinked to original sources

Safe feeding practices for infants and young children.

OBJECTIVE: To review local and overseas experience of food asphyxia in children and to examine aspects of safe childhood eating practices. METHODOLOGY: Inpatient separation information data for childhood hospital admissions in South Australia were searched for episodes of food-induced airway obstruction and case records of the Department of Histopathology at the Women's and Children's Hospital were searched for cases of fatal food asphxia. RESULTS: While other forms of injury to young children appear to be declining in numbers, episodes caused by choking on food have remained relatively constant. The increase in average length of hospital stay (from 2.8 days in 1989-90 to 5.2 days in 1993-94) also suggests that the episodes have been more severe. Two fatal cases were also found. CONCLUSIONS: Choking due to food inhalation is a problem with potentially fatal consequences. Young children are particularly at risk as they have immature dentition and control of swallowing, and lack experience of food. Although young children should avoid potentially dangerous foods such as raw carrot sticks and raw apples, certain currently available information packages for parents recommend these foods.

Airway Obstruction↗

General management in the NHS: three views from the trenches.

Views from three general managers focus respectively on the impact of the Griffiths changes after five years; how 'success' in general management may be evaluated; and the changing nature of central-local relationships. At district level, the job of DGM has changed much more than was expected and the demands have greatly increased. These developments have resulted in increased satisfaction for the general manager and a desire to achieve results. 'Success' in general management is an elusive concept. There are many perceptions of success. For general managers, success may be reduced to a struggle for survival. Ultimately, success needs to be extended beyond short-term goals and to be concerned with shaping the longer term future. Central-local relationships have, in many ways, changed little. The major criticism of the centre by the service remains much the same as before the Griffiths reforms-the lack of central leadership and direction. Regions are perceived as part of the centre by districts and units. There is much to be done to make central-local relationships more creative and supportive.

Administrative Personnel↗

CT evaluation of extrahepatic disease in patients with metastatic colorectal carcinoma receiving hepatic arterial chemotherapy.

Computed tomography (CT) of the abdomen and pelvis in 88 patients with hepatic metastases from colorectal carcinoma undergoing hepatic arterial chemotherapy has been reviewed. Extrahepatic disease was present as determined by CT examination in 83 (94%). Tissue proof was available for 23 sites in 19 patients, with the most common sites being retroperitoneal lymph nodes (5), lung (3), abdominal wall (3), and peritoneum or mesentery (3). Clinical proof was obtained for 78 sites in 51 patients, the most common being lung (20), retroperitoneal lymph nodes (19), and porta hepatis lymph nodes (12). CT detection of extrahepatic disease is useful, since its presence has prognostic and therapeutic implications.

Antineoplastic Agents↗

Crohn disease in the elderly.

During the past 2 years, we have encountered 14 patients whose onset of clinical symptoms of Crohn disease occurred after the age of 50, accounting for 14% of all Crohn disease patients studied in our department during this period. Most patients presented with diarrhea, abdominal pain, or perianal disease, and many also had anemia or rectal bleeding. The disease occurred slightly more often in the colon (n = 10), although many patients had terminal ileal disease (n = 7). The radiographic appearance was similar to that of Crohn disease in younger patients, with ulceration, fistula, and stricture formation. Occasionally, the disease mimics neoplasia or diverticulitis. Extraintestinal complications were also evident, with one patient each with renal calculi and ankylosing spondylitis. The occurrence of Crohn disease in the elderly is not uncommon, and a prompt diagnosis is important so that proper therapy can be initiated.

Abdomen↗

Child abuse.

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Australia↗

Child abuse.

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Australia↗

N-Nitroso-3-hydroxypyrrolidine in fried bacon and fried out fat.

N-Nitroso-3-hydroxypyrrolidine was extracted from fried bacon and fried-out fat with water:methanol (3:2). After elimination of residual nitrite with ammonium sulfamate, the nitrosamine was removed from the water:methanol by continuous extraction with dichloromethane. Identification was accomplished by conversion of N-nitroso-3-hydroxypyrrolidine to the trimethylsilyl derivative followed by separation on a capillary column and characterization by gas chromatography-mass spectrometry. Quantification and recovery studies were conducted without derivatization. Concentrated dichloromethane extracts were analyzed using a gas chromatographic-thermal energy analyzer system. Recovery of N-nitroso-3-hydroxypyrrolidine from fried bacon and fried-out fat was 62 and 63%, respectively. Five commercial samples of fried bacon contained 0.4-3.9 ppb, while the fried-out fat contained 0.3-2.2 ppb N-nitroso-3-hydroxypyrrolidine.

Animals↗

Management of infant sleep problems in a residential unit.

Torrens House provides a short residential programme for families with a baby (8-12 months of age) identified by parents as having a sleep problem such as waking frequently at night and being difficult to settle. The programme involves the promotion of infant self-settling by the use of a controlled crying technique, together with wrapping, cessation of night feeds and establishment of a day-time routine. Twenty families (with 23 babies) were followed through the programme and for 3 months afterwards. There were significant decreases in the number of times the babies woke, the number of night-feeds and the length of time awake at night at 1 month follow-up, with a reduction in depressive symptomatology of the parents and a perceived improvement in their infants' behaviour. Twenty of the 23 babies were sleeping well at 3 month follow-up.

Behavior Therapy↗

Child abuse.

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Australia↗