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Biomedical subjects

J Bar-Ziv

Publications and source records attributed to J Bar-Ziv.

At least 91 records · Page 5Linked to original sources

Computed tomography in adult intussusception.

Computed tomographic (CT) changes of intussusception include the early target mass with fascial planes around the mass retained; with progress and bowel wall thickening, the characteristic mass with layering effect occurs (i.e., areas of high density with curvilinear low-density zones). Traction on the associated mesenteric vasculature may be noted. Scattered air-fluid levels indicate the associated presence of bowel obstruction. As edema of the bowel progresses, the layering effect is obscured, and the compromised bowel assumes an amorphous shape surrounded by intraperitoneal fluid. The presence of intramural air is indicative of vascular compromise of the intussuscepting bowel.

Adult↗

Sarcoma botryoides of the common bile duct: preoperative diagnosis by coronal CT and PTC.

Sarcoma botryoides of the extrahepatic bile ducts is a rare cause of obstructive jaundice in the pediatric population. It is rarely diagnosed preoperatively. We present a case of this tumor which was diagnosed by ultrasound, computerised tomography and PTC. Coronal CT sections were particularly useful in demonstrating the relationship of the tumor to the porta hepatis, pancreas and duodenum.

Child, Preschool↗

A steroid derivative (RU 5135) exhibits epileptogenicity in the presence of deficient blood-brain barrier.

A hypothesis was tested that epileptic spiking, induced by systemic administration of a steroid derivative (RU 5135), may be associated with surgery-related cortical damage rather than epileptogenicity of the agent. Cumulative doses of the drug were given to rats and rabbits. The lasting quasi-periodic seizure discharges were always seen initially only under an epicortical electrode implant. Brain damage in inflicted by such an electrode was confirmed anatomically (by assessing the area of lesion) and noninvasively (by showing contrast-induced enhancement of CT brain images in the hemisphere homolateral to epicortical electrodes). The threshold of epileptic spiking varied inversely with the area of cortical damage inflicted by the electrode. In a number of cases no spiking was obtained from the hemisphere with nonpenetrating (intraosteal) electrodes. We caution that a breach of the BBB caused by conventional surgery in rodents can make a benign drug appear as excessively toxic thereby discrediting potentially useful compounds.

Androstanes↗

Quadriparesis in the Laurence-Moon-Biedl-Bardet syndrome: case report.

A 36 year old patient known to suffer from the Laurence-Moon-Biedl-Bardet syndrome (LMBBS) developed spastic quadriparesis. The typical features of the syndrome, presented by this patient were polydactyly, obesity, hypogonadism, retinitis pigmentosa and relative mental retardation. Severe spinal cervical and lumbar canal stenosis imaged by plain X-rays and computerised tomography was found. Magnetic resonance imaging showed significant atrophy of the spinal cord, indicating that the cause of the quadriparesis was cervical myelopathy. The patient underwent laminoplasty with some improvement.

Adult↗

Study of the normal and insufficient velopharyngeal valve by the "Forced Sucking Test".

A thorough assessment of the velopharyngeal (VP) closure dynamics is important for therapeutic planning in patients with nasal speech. An additional diagnostic tool to the standard endoscopic examination of the VP valve, the "Forced Sucking Test" (FST) is presented. In this study, 110 patients with a normal VP valve and 40 patients with VP insufficiency were subjected to a comprehensive endoscopic examination. When existent, Passavant's ridge clearly appears in 80% of these cases during the FST. This is advantageous, since the ridge is often unseen during routine nasendoscopy. Passavant's ridge appears indistinguishable in shape and level during speech and FST. During FST, the bulge of the uvular ridge is clearly seen on the flat or concave nasal surface of the velum. In cases of diastasis of the velar musculature, the midline V-defect of the velum is clearly seen. The test is particularly important in children with concomitant adenoid hypertrophy. The findings are discussed in terms of their implications for the anatomy and physiology of the VP valve. FST is recommended as an additional and complementary part of the endoscopic examination of the VP valve.

Adult↗

Computerized tomographic recognition of visceral pleural changes.

Pathology of the visceral pleura seen by CT of the lung can be separated from the underlying lung parenchyma by using appropriate CT window viewing settings. A wide window setting permits both pleura and lung parenchyma to be examined simultaneously. The use of mediastinal window setting (i.e., soft tissue) showed the smooth inner surface of parietal pleural fibrosis or plaque formation lying parallel or convex to the associated rib cage, whereas the thickened or calcified visceral pleura had an irregular inner surface with single or multiple protrusions penetrating the underlying lung substance and retraction of the associated pathological visceral pleural surface. We present cases of tuberculous calcified visceral pleura, a talc pleuritis and carcinoma abutting on the interlobar fissure, and clearly demonstrate the CT features.

Calcinosis↗

[Duodenal duplication cyst].

Duodenal duplication cysts are rare and are usually found in neonates or young children who present with obstructive symptoms. It accounts for 4-12% of all duplications in the gastrointestinal tract. The rate of other developmental abnormalities has been reported as high as 38%. In few instances have duodenal duplication cysts been described in adults. A case of duodenal duplication cyst in a 46-year-old woman is presented. The diagnosis was established preoperatively by computerized tomography and ultrasound examination.

Cysts↗

[Primary iliopsoas abscess in children].

Primary iliopsoas abscess is a relatively rare disease occurring mainly in children. Since it simulates more common conditions, delay in diagnosis is almost the rule. In 2 children it simulated acute appendicitis, but in both cases a normal appendix was removed. In a third child it led to the diagnosis of right sacroiliitis, and antibiotics were given for several weeks. Ultrasound examinations in all 3 failed to reveal the diagnosis, which was reached by CT scan. The latter is the method of choice for diagnosis and is of aid in deciding on the best route for drainage.

Abscess↗

Possible heterogeneity in spondyloenchondrodysplasia: quadriparesis, basal ganglia calcifications, and chondrocyte inclusions.

We report on 6 patients with short stature and progressive enchondromatous-like changes of the vertebral bodies and the metaphyses of the long bones. Parental consanguinity was observed in 5 of 6 cases, supporting autosomal recessive inheritance. In spite of the similarity in radiographic changes and body proportions, genetic heterogeneity is suggested by the presence of CNS calcifications in 3 patients. Two of the latter had progressive quadriparesis. We tentatively classified these patients into 2 provisional types. An iliac crest biopsy in one of the patients with "type I" disease did not demonstrate enchondromatosis. Light and transmission electron microscopic studies demonstrated large cisterns and small inclusion bodies containing a flocculent material within the rough endoplasmic reticulum of the chondrocytes. Based on the histological and radiographic findings, we propose to classify these conditions among the spondylometaphyseal skeletal dysplasias.

Adolescent↗

Direct coronal CT scanning of tracheo-bronchial, pulmonary and thoraco-abdominal lesions in children.

Direct coronal plane CT demonstration of the tracheobronchial and pulmonary anatomy is possible. Large gantry openings easily accommodate patients in a sitting or semiprone position without the need for attaching a seat device to the table top. A technique is described for examining the patient using Elscint 1800 and 2400 CT units, with a net gantry angulation of 60-80 degrees to the chest, with resulting good quality direct coronal CT imaging. Our experience includes more than a hundred pediatric patients that have been examined, displaying diverse tracheobronchial, pulmonary and thoraco-abdominal lesions. The technique is safe and comfortable to the patients and is easy to perform.

Adolescent↗

Adequacy of the International 10-20 electrode system for computed neurophysiologic topography.

The adequacy of the International 10-20 System is reviewed in light of demands imposed on the accuracy of lead placement by improvements in spatiotemporal brain electrical activity mapping technology. Computed tomography (CT) and magnetic resonance imaging (MRI) studies reveal that the most frequent sources of inaccuracy of electrode locations are difficulties in defining the inion, variance in the anatomy of the occipital bone, inconspicuous sagittal deformities, variance of sulcal pattern, and brain width asymmetries. Owing to these factors, electrodes placed bilaterally and equidistant from the nasion-inion line may not be homotopically located. Therefore, the authors suggest that practitioners who employ the 10-20 System in order to gain precise and more individualized laterality information do so with extreme caution until the range of placement and interpretative errors is more precisely determined using CT/MRI-assisted EEG.

Brain↗

Pineal germinoma with unilateral blindness. Seeding of germinoma cells in optic nerve sheath.

A 13-year-old boy presented with blindness and loss of the papillomacular bundle in the left eye, bilateral papilledema sparing the area of axonal loss, and Parinaud's syndrome. Computerized tomography (CT) revealed an enlarged kinked left optic nerve and enlarged optic canal as well as a tumor in the pineal area producing hydrocephalus. Magnetic resonance (MR) scans showed multiple spinal metastases. The histological diagnosis was germinoma. On completion of four courses of chemotherapy with cis-platin, vinblastine, and bleomycin, repeated CT of orbita and MR imaging of the spine demonstrated the disappearance of the tumor surrounding the left optic nerve and of the spinal metastases. This is believed to be the first case report of seeding of germinoma into the perioptic arachnoid space.

Adolescent↗

EEG asymmetries may be affected by cranial and brain parenchymal asymmetries.

The plagiocephaly index, an index that reflects an underlying anatomic asymmetry of the brain, was assessed in ten schizophrenic patients and its values were correlated with the lateral distribution of quantitatively evaluated EEG. The correlations between the index and alpha power at F7 were significant, positive for frontal asymmetry (frontal bulging) and negative for occipital flattening. We then studied ten normal subjects in an attempt to illuminate the contribution of several cephalic and cranial variables to the imbalance of alpha-afterdischarges (AD) of VEP recorded at O1-O2. The asymmetry index of AD was computed and correlated with asymmetries of CT-derived measures of occipital bone thickness, occipital lobe width, mastoid area, and sulcal asymmetry (the asymmetry of intraparietal sulcus location from the longitudinal fissure). With the exception of the sulcal variable all measures significantly covaried with alpha AD. These findings caution that it may be important to determine cranial and brain parenchymal asymmetries where brain laterality is pertinent to studies of EEG.

Adolescent↗

Bilateral alpha distribution and anatomic brain asymmetries.

The parieto-occipital (PO) index of the VEP alpha-afterdischarge (AD) was assessed bilaterally in normal subjects in three successive sessions separated by one-three weeks with two within-session retests. Correlations between PO values and asymmetries of occipital and parietal width, mastoid area, basal angle, cephalic, and plagiocephaly indices were established in simple correlation and stepwise multiple regression analysis. Occipital width, notably in the right hemisphere correlated reliably with the PO index in relaxed wakefulness and the vigilance task. The population having normal and reversed occipital brain width is predicted to have different parieto-occipital AD distribution. Some errors of lateral EEG measurements introduced by slant cranial deformity are discussed in order to call attention to the fact that anatomy-related lateral EEG changes may masquerade as cognition-related asymmetries.

Adolescent↗

The use of a modified direct coronal computed tomographic technique for assessing thoraco-abdominal problems.

A modified simple technique for direct computed tomographic (CT) coronal body scanning is described and illustrated with relevant cases. Problems related to partial volume effect are eliminated and the anatomical relationship of organs are defined with easy compartmentalization of associated pathology. Spatial resolution is better than with multiplanar reformatted images. The method is particularly effective in demonstrating thoraco-abdominal pathology.

Aged↗