Search PubMed⌕ Search

Biomedical subjects

J Bailey

Publications and source records attributed to J Bailey.

At least 253 records · Page 14Linked to original sources
PubMed1969

Vibration as a reinforcer with a profoundly retarded child.

Data are presented which indicate that lever-pressing behavior of a profoundly retarded child could be reinforced by the contingent application of vibratory stimulation for each response. With vibration available 24 hr per day, no decrement in daily rate of responding for vibration was seen over a three-week period. Suggestions are made for further use of this finding in working with the profoundly retarded.

Journal Article↗
PubMedDate not supplied

Postpartum and postabortion use of the TCu-220C and Lippes Loop: A comparative study.

The postinsertion experience of 274 women with the TCu-220C and 522 women with the Lippes Loop in a university hospital family planning program in Bogotá, Colombia, has been studied by a life-table method. Pregnancy and continuation rates are similar for both devices. Although the expulsion rate of the TCu-220C is significantly lower than that of the Loop up to 12 months, higher removal rates for the TCu-220C account for the similarity in overall continuation.

Abortion, Spontaneous↗
PubMedDate not supplied

Astronomical sources of circularly polarized light and the origin of homochirality.

Possible astronomical sources of ultraviolet circularly polarized light (UVCPL) which might be responsible for enantiomeric selection in interstellar organic molecules are considered, Synchrotron radiation from magnetic neutron stars has been suggested as a possible source of UVCPL. However, synchrotron radiation in these situations is not predicted to be strongly circularly polarized. Very few such sources show optical synchrotron radiation and in the few that do circular polarization has not been observed. Magnetic white dwarfs and white dwarf binaries (Polars) can be highly circularly polarized but any effect on molecular clouds and star formation regions must rely on rare chance encounters. Recent observations show that substantial levels of circular polarization are present in reflection nebulae in star formation regions. This mechanism produces polarized light exactly when and where it is needed in regions where star formation is occurring and organic molecules are known to be present.

Amino Acids↗
PubMedDate not supplied

The DNA sequence and comparative analysis of human chromosome 20.

The finished sequence of human chromosome 20 comprises 59,187,298 base pairs (bp) and represents 99.4% of the euchromatic DNA. A single contig of 26 megabases (Mb) spans the entire short arm, and five contigs separated by gaps totalling 320 kb span the long arm of this metacentric chromosome. An additional 234,339 bp of sequence has been determined within the pericentromeric region of the long arm. We annotated 727 genes and 168 pseudogenes in the sequence. About 64% of these genes have a 5' and a 3' untranslated region and a complete open reading frame. Comparative analysis of the sequence of chromosome 20 to whole-genome shotgun-sequence data of two other vertebrates, the mouse Mus musculus and the puffer fish Tetraodon nigroviridis, provides an independent measure of the efficiency of gene annotation, and indicates that this analysis may account for more than 95% of all coding exons and almost all genes.

Animals↗
PubMedDate not supplied

Interventions/Wilmer: a continuum of care for substance abusers in the criminal justice system.

This article describes a 300-bed substance abuse treatment program that is part of a continuum of care focused on preventing drug and criminal recidivism in substance abusing criminals incarcerated in Dallas County, Texas. It is the product of a joint effort of the judiciary, the Dallas County Supervision and Corrections Department, the State of Texas Criminal Justice Division, and Interventions Co., a not-for-profit treatment provider. The program is rooted in over 25 years of treatment experience and incorporates therapeutic community (TC) technology combined with 12-Step programming, behavior modification, job training (having a job is required for graduation), educational, and medical/psychiatric elements. Treatment is conceived as part of a continuum of care to provide substantial and sustained support for the inmate in the difficult process of adapting to the community post incarceration. Treatment plans are individualized and are based on an extended workup in which the individual's status in a number of domains is assessed. Specialized services, such as transportation and childcare, facilitate recovery. Once in the community, urine monitoring, groups, and counseling continue. The program is beginning its fourth year of operation and approximately 600 inmates have started the program. A formal evaluation is in process.

Adult↗
PubMedDate not supplied

Flumazenil in alcohol withdrawal: a double-blind placebo-controlled study.

The purpose of the present study was to study gamma-aminobutyric acid (GABA)-A receptor function in alcohol-dependent subjects during withdrawal, using the benzodiazepine antagonist flumazenil. In particular, we wanted to examine the hypotheses that an endogenous inverse agonist ligand at the GABA-A benzodiazepine receptor (GBzR) is active during withdrawal (in which case flumazenil should be anxiolytic), or whether chronic alcohol intake results in a shift in sensitivity of the receptor in the inverse agonist direction (in which case flumazenil should be anxiogenic). Results from 15 alcohol-dependent subjects in a double-blind placebo-controlled cross-over study showed that flumazenil was neither anxiolytic nor anxiogenic, although withdrawal scores were reduced during the course of the study. The fact that flumazenil was not anxiogenic, as it is in panic disorder, suggests that the GBzR is functioning differently in these two clinically similar conditions.

Adult↗
PubMedDate not supplied

Decreasing nosocomial urinary tract infection in a large academic community hospital.

Urinary Tract Infection (UTI) is the second most prevalent complication at Lehigh Valley Hospital and Health Network, occurring in 3% of all patients admitted over a 12-month period and contributing to a significant increase in costs. Utilizing data from CareScience's Care Management System, an online decision support tool, in conjunction with hospital laboratory data, and without manual chart review, approximately 20% of all UTIs diagnosed were found to be potentially nosocomial, and were often treated with an expensive broad-spectrum antibiotic. A multidisciplinary hospital committee developed interventions to study and address these findings. The National Nosocomial Infection Surveillance program was initiated on selected units of the hospital; strict catheter placement guidelines and a postoperative urinary retention protocol were developed to minimize catheter use and dwell time, a cost-benefit analysis was conducted, antibiotic use for UTIs was evaluated, and system-wide education was conducted for physicians, residents, and nurses.

Anti-Bacterial Agents↗