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Biomedical subjects

J Badoual

Publications and source records attributed to J Badoual.

102 records · Page 6Linked to original sources
PubMedDate not supplied

[Comparison between the number and nature of fecal clostridia and other risk factors implicated in the intestinal pathology of newborn infants].

One-hundred and fifteen infants aged 1 to 31 days from two intensive-care units were grouped into 6 classes according to clinical criteria (enterocolitis with or without anatomopathological examination and pneumatosis intestinalis, "haemorrhagic colitis", acute diarrhoea or absence of intestinal disorders). The total number of viable bacteria, the number of Clostridium and, in some cases, the presence of rota- and/or coronavirus were determined in their stools. The incidence of Clostridium in the stools of infants with enterocolitis (with or without pneumatosis intestinalis) or haemorrhagic colitis was not significantly different from that of infants without intestinal disorders, whereas stools of infants with acute diarrhoea less often contained Clostridium than those of other infants. C. butyricum, C. difficile, C. perfringens, C. tertium, and C. sordellii were identified. Correspondence analysis comparing the variable, "clinical profile", with 23 other variables, suggested that the variables of gemellity, a birthweight below 1900 g, a gestational age of less than 35 weeks, respiratory distress, umbilical catheterization and a Clostridium count above 10(7)/g at the onset of clinical signs, i.e. between 8 to 12 days of age, were linked to the clinical profile of necrotizing enterocolitis with pneumatosis intestinalis. Conversely, the absence of gemellity, a high birthweight and gestational age, the absence of respiratory distress or umbilical catheterization, the onset of diarrhoea within 8 days, and the presence of rota- and/or coronavirus in the stools were linked with a clinical profile of acute diarrhoea.

Birth Weight↗
PubMedDate not supplied

[African histoplasmosis. A case].

The case reported concerns a 12 year-old girl, native of the Cameroons, hospitalized in France for the treatment of the most severe disseminated type of African histoplasmosis (Histoplasma duboisii). In addition to a severe infectious syndrome, the child presented with 3 associated typical involvements: diffuse lymphadenopathy, skin lesions consisting of nodules of the face and trunk and suppurative osteo-articular lesions with an impressive radiological appearance: extensive bone lysis and metaphyseal fractures, without any sign of bone reconstruction, even after several months of treatment. This is rare a disease, but one that should be recognized, especially in its onset localized form, in a patient presenting with infectious osteoarthritis with a torpid evolution leading to the diagnosis of tuberculous or pyogenic infection, or even of osteosarcoma. The disseminated lesions may be difficult to distinguish from the multifocal bone lesions of sickle-cell disease osteomyelitis.

Cameroon↗
PubMedDate not supplied

Lung transfer factor for CO at rest in normal children by a steady-state method.

Lung transfer for CO (TLCO) was measured at rest in 94 normal children (47 boys and 47 girls) whose ages ranged from 3.5 to 16 years. A steady-state method, using a technique of alveolar sampling based on the equality of the mean expiratory and alveolar respiratory quotients, was employed. Highly significant correlations, statistically different for boys and girls, were fond between TLCO and standing height. TLCO was also linearly correlated with the functional residual capacity--the only pulmonary volume measurable in very young children--but without any sex difference. A multiple linear regression relates TLCO to FRC and height. Variance analysis shows the preponderant influence of FRC.

Adolescent↗