Combination chemotherapy and radiation therapy of squamous cell carcinoma of the head and neck.
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Carcinoma, Squamous Cell↗
Biomedical subjects
J B Snow
Publications and source records attributed to J B Snow.
Effects of furosemide and ethacrynic acid on the endocochlear direct current potential in normal and kanamycin sulfate-treated guinea pigs.
The effects of loop diuretics on the endocochlear direct current (DC) potential and the effective electrical resistance of the cochlear partition were studied. The effective electrical resistance was increased, and the endocohlear DC potential was decreased. The decrease in the endocohlear DC potential must not be caused by breaks in the electrical insulation of the cochlear partition. With loop diuretics the endocochlear DC potential decreased less in guinea pigs treated with kanamycin sulfate than it did in the control group. Two interpretations of these phenomena are presented.
Animals↗
Hypoparathyroidism secondary to surgery for carcinoma of the pharynx and larynx.
Hypoparathyroidism occurs secondary to surgery for carcinoma of the pharynx and larynx in which a total thyroidectomy is required. The indications for partial and total thyroidectomy are presented. Hypoparathyroidism is an important and complex problem with the clinical presentation ranging from tetany to latent chronic hypoparathyroidism. Serum calcium, phosphate, magnesium, and protein levels are important parameters to monitor. A therapeutic strategy is presented and its complications are discussed. The role of magnesium in calcium metabolism is emphasized.
Adult↗
Hearing loss of a central type secondary to carbon monoxide poisoning.
The effect of carbon monoxide poisoning on the threshold sensitivity of the responses from the auditory cortex, inferior colliculus, and cochlea to acoustic stimuli in guinea pigs was studied. The toxicity of carbon monoxide is believed to be secondary to tissue hypoxia and is partially reversible. Loss of auditory threshold sensitivity in carbon monoxide poisoning is most prominent at the auditory cortex. The loss of sensitivity at the inferior colliculus is the next most severe. There is no loss of sensitivity at the cochlea. The relative vulnerability of the central auditory pathway to carbon monoxide poisoning as compared with the end organ is demonstrated.
Animals↗