Providers beware: HMOs may control your destiny.
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Biomedical subjects
Publications and source records attributed to J B Riley.
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Potential sources of gaseous microemboli during cardiopulmonary bypass are varied. However, it is known that membrane oxygenators generate fewer gaseous microemboli than bubble oxygenators and that bubblers cannot utilize arterial heat exchange without generating significant gaseous microemboli during rewarming. A membrane oxygenator utilizing simultaneous gas and heat exchange raises the concern that concurrent gas and heat exchange would result in a higher production of gaseous microemboli compared to conventional venous heat exchange devices. This in vitro study compared venous, simultaneous, arterial and control (venous) heat exchanger gaseous microemboli counts during rewarming. No significant difference was found between the four heat exchangers when comparing inlet and outlet gaseous microemboli counts. This in vitro study suggests that there is no difference in gaseous microemboli generation when varying the position of the heat exchanger in the extracorporeal circuit incorporating a microporous membrane oxygenator.
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This study confirms and extends the available information about cardiac surgery in patients with chronic renal failure. With appropriate precautions, CABG and valve repair can be carried out in these patients without significant increase in operative mortality or morbidity as compared to patients with normal renal function. However, these patients remain susceptible to accelerated atherosclerosis in native vessels as well as bypass grafts and to complications (thromboembolism, infection) of prosthetic valves. Accordingly, while these patients are often significantly improved as a result of their cardiac surgery, long term outlook is guarded.
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Three devices used to measure hemoglobin oxygen saturation in the extracorporeal circuit were studied and compared to a control. The Baxter Bentley OxySat, Oximetrix Accusat, and Radiometer ABL4 blood gas monitor were compared to a control, the IL 282 Co-Oximeter. Fifty-one sample points were obtained during all phases of cardiopulmonary bypass with results as follows: table: see text. The Accusat was found to be a statistically more accurate means of monitoring hemoglobin oxygen saturations during cardiopulmonary bypass than the ABL4 and the OxySat. All devices had significant correlation with the control and with each other.
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