[Medical treatment of mediastinal perforation of Barrett's ulcer].
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Aged↗
Biomedical subjects
J B Nousbaum
Publications and source records attributed to J B Nousbaum.
[Pancreatic sarcoidosis].
The authors report the case of a 30 year-old man with previous history of sarcoidosis, who presented with a painful infiltration of the pancreas. A review of the literature showed that symptomatic pancreatic sarcoidosis was uncommon, since only 8 other cases have been reported. Pancreatic involvement is frequently associated with hepatic infiltration (5/6 cases). Exocrine or endocrine dysfunction are possible. Diagnosis is made only at exploratory laparotomy. Prognosis is good. Steroid therapy is indicated in this peculiar type of pancreatitis, because of its long-range effectiveness on the outcome of the disease.
Acute Disease↗
[2 unusual manifestations of LAV-HTLV virus infection: BCGitis and pulmonary chickenpox].
A patient with AIDS developed local complications of BCG vaccination and disseminated chickenpox with severe pneumonia. This cas suggests that AIDS patients should not receive BCG vaccination and that adults with severe chickenpox should be investigated for LAV/HTLV III virus carriage.
Abscess↗
[Spontaneous peritonitis in systemic lupus erythematosus].
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Adult↗
Interferon and ursodeoxycholic acid combined therapy in chronic viral C hepatitis: controlled randomized trial in 203 patients.
AIMS: This prospective randomized trial was carried out in order to determine whether the long-term administration of ursodeoxycholic acid after discontinuation of interferon had any beneficial effect on the clinical course of hepatitis C virus infection. METHODS: Enrolled in the study were 203 patients with chronic active hepatitis C. They were all given: interferon alpha-2a (3 MU subcutaneously thrice a week) and ursodeoxycholic acid (10 mg/kg/day) for 9 months. At month 9, biochemical responders only were randomized into ursodeoxycholic acid treatment or placebo for 12 additional months (double blind study). RESULTS: At the end of interferon therapy, 71 patients (37%) were virological responders and 107 (56%) patients were biochemical responders and were randomized: 54 into the ursodeoxycholic acid group and 53 into the placebo group. Sustained response was evaluated 12 months after withdrawal of interferon. Sustained biochemical and virological responses were, respectively, 30% and 22% in the ursodeoxycholic acid group and 46% and 32% in the placebo group, which did not significantly differ. Histological evolution of fibrosis and necrotic inflammatory activity were similar in the two groups. CONCLUSION: Continuation of ursodeoxycholic acid therapy after withdrawal of interferon in patients with end-of-treatment response did not result in any significant improvement either in the maintenance of response to interferon or in liver histology.
Adolescent↗
[Angina-like chest pain: physiopathology, diagnostic measure and treatment].
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Angina Pectoris↗
[Saturnine colic and hemolytic anemia due to ingestion of solid lead. Apropos of a case].
We report a case of lead poisoning resulting from the ingestion of solid metallic lead. A 24 year old patient was admitted for abdominal pain and microcytic anemia. Review of the literature suggests that clinical manifestations of chronic poisoning by solid lead in adults are extremely rare. Their misreading can lead to erroneous diagnose.
Adult↗