Effectiveness of vaginal cones in treatment of urinary incontinence.
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Biomedical subjects
Publications and source records attributed to J B Metcalfe.
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A neonate with infantile polycystic kidney disease underwent Tc-99m DMSA imaging. The pattern of uptake in infantile polycystic disease is different from the multiple cystic lesions reported in the literature for adult polycystic kidney disease. The infantile pattern of uptake shows large kidneys with diffuse, symmetric localization of the radiopharmaceutical, which seems to be characteristic and may be pathognomonic of the disease process.
Sixty-four patients with multiple sclerosis and associated symptoms of neurogenic bladder dysfunction underwent urodynamic evaluation. The most common symptoms were urgency, incontinence, and frequency which did not correlate with urodynamic findings. Cystometrography demonstrated hyperreflexic bladders in 78 per cent and areflexic bladders in 20 per cent of patients. In those patients with hyperreflexia, voiding cystourethrography revealed poorly sustained uninhibited contractions associated with ineffective bladder emptying in 50 per cent, well-sustained contractions in 38 per cent, and detrusor-sphincter dyssynergia in 12 per cent. Therapy consisted of intermittent catheterization, pharmacologic manipulation, or transurethral resection of the external sphincter, according to urodynamic evaluation.
Genitourinary tumors account for half of all documented cases of pseudohyperparathyroidism. The treatment of hypercalcemia is directed toward immediate correction of the electrolyte imbalance and long-term control. These goals are accomplished with volume repletion, calcium normalization and removal of the tumor. Effective therapy includes saline infusion and furosemide. Additional control is obtained with phosphates and/or indomethachin. In refractory cases actinomycin-D or mithramycin is helpful. The first reported case of urethral cancer and second reported case of testicular seminoma producing this syndrome are added to the literature.
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