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Biomedical subjects

J B Lauritzen

Publications and source records attributed to J B Lauritzen.

47 records · Page 3Linked to original sources
PubMed1986

The association between drinking and smoking habits among conscripts in the Danish Navy and Army.

In 1982 an alcohol and tobacco questionnaire was given to Danish conscripts on random weekdays in the first two weeks of call-up. The conscripts were asked about the previous day's consumption of alcohol and tobacco. In the navy 94.4% (N = 162) and in the army 92.0% (N = 514) answered the questions. Both smoking and drinking in the navy were found to be more prevalent than in the army, whereas the habits among conscripts in the army and in the civilian population were identical. In the army length of education was found to be inversely related to drinking and smoking, whereas in the navy education did not seem to influence smoking or drinking habits. In the army increasing amounts of drinking were associated with higher prevalences of light to heavy smoking and vice versa. In the navy only heavy drinking was strongly associated with a pronounced rate of heavy smoking. The difference seen between the navy and the army in tobacco and alcohol habits could not be explained by differences in age or level of education. Some other sociological, psychological and life style factors may be involved. We find it relevant to pinpoint high risk populations regarding excessive alcohol and tobacco consumption, so that rational prophylaxis or intervention might be effectuated. Health education programmes ought to contain information about the illnesses of both excessive alcohol and tobacco consumption, as these habits are closely related.

Adolescent↗
PubMed1982

Gastric inhibitory polypeptide (GIP) and insulin release in response to oral and intravenous glucose in uremic patients.

Eight patients with advanced renal failure of long duration were studied 1 day after hemodialysis. A 50 g oral glucose load (OGTT) and an intravenous glucose infusion (IVGI), giving the same plasma glucose profile as the OGTT, were carried our in order to study the relation between Gastric Inhibitory Polypeptide (GIP) plasma levels after oral glucose and the insulin release during OGTT and IVGI. The plasma GIP increase during OGTT was significantly elevated compared to a group of eight healthy volunteers. The insulin potentiation during OGTT in relation to GIP was significantly depressed in the uremic patients. It is proposed that a factor of intestinal origin is released during intake of carbohydrates, which blocks the B-cell response to the combined glucose-GIP stimulus. Alternatively, the concentrations of plasma GIp measured have included GIp fragments without insulin releasing capability.

Administration, Oral↗
PubMed1982

Superficial eosinophilic squamous epithelial cells in vaginal smears from postmenopausal women.

19 500 vaginal smears from women aged 20-90 years were examined from August 1976 to November 1979. 3 000 were from women more than 55 years of age. 146 of these had smears with an increased proportion of superficial eosinophilic squamous epithelial cells (SESEC). The smears were divided into four groups, A-D with 0-25%, 25-50%, 50-75% and 75-100% of SESEC of the examined squamous epithelial cells. 39% of the 146 with increased proportions of SESEC were either undergoing treatment with estrogenic hormones, or else the possibility of estrogenic influence could not be ruled out. In group D the possibility of an estrogenic influence was more pronounced, here found to be 67%. In 32% of the 146 cases we believe that these cells were possibly the result of changed anatomical conditions in the cervix/vagina. Such an explanation seems most frequently probable in groups A and B. In 5% of the 146 cases the cells appeared changed, as can be seen in trichomoniasis. In 21% the discovery of the cells could not be explained. Finally, no explanation could be found for 5% in group D.

Age Factors↗
PubMed1982

Gastric inhibitory polypeptide and insulin release in response to oral and intravenous glucose in coeliac disease.

Eight patients with biopsy-verified coeliac disease were investigated after remission on a gluten-free diet. A 50-g oral glucose load (OGTT) and an intravenous glucose infusion (IVGI) giving the same plasma glucose profile as the OGTT were carried out. The relation between gastric inhibitory polypeptide (GIP) plasma levels after oral glucose and the insulin release during OGTT and IVGI were studied. Plasma GIP concentration in the fasting state and the increase in plasma GIP during OGTT were significantly lower than in a group of eight healthy volunteers. However, the insulin potentiation during OGTT, the incretin effect, was normal. The results indicate the existence of other incretins than GIP. These are probably released from the distal small bowel in patients with coeliac disease.

Adult↗