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Biomedical subjects

J B Jacobs

Publications and source records attributed to J B Jacobs.

At least 91 records · Page 5Linked to original sources
PubMed1975

Ultrastructural changes in livers of tumour bearing rats.

An ultrastructural study of the livers of rats bearing transplanted mammary carcinomata from 4 to 12 weeks after transplantation revealed changes mainly in cytoplasmic structure of hepatocytes. The significant findings were pleomorphism of mitochondria, presence of large number of myelin figures, marked increase in microbodies, dilatation of rough endoplasmic reticulum, proliferation of smooth endoplasmic reticulum, intracytoplasmic cholesterol clefts and absence of increase in lysosomes. These alterations have been compared with that of others who have used different animal model systems to study the effect of tumour in livers of host. Centrioles in Küpffer cells are described for the first time in this study.

Animals↗
PubMedDate not supplied

Evaluation of the frontonasal duct in frontal sinus fractures.

Successful management of frontal sinus fractures depends on correct identification of structural pathology, which may lead to inflammatory complications. Obstruction of the frontonasal duct is a significant factor predisposing to such complications and its evaluation is thus critical in the management of these fractures. Specific radiographic CT criteria and an intraoperative dye irrigation test are presented to determine the likelihood of frontonasal duct injury. Eighteen cases of frontal sinus fractures are reviewed, which have been treated based on these principles. A scheme is presented outlining the management of frontal sinus trauma using these methods.

Frontal Sinus↗