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Biomedical subjects

J B Howell

Publications and source records attributed to J B Howell.

90 records · Page 5Linked to original sources
PubMed1968

Relation between airways obstruction and CO2 tension in chronic obstructive airways disease.

The relationship between the F.E.V.(1) as an index of airways obstruction and Pco(2) as an index of hypoventilation was investigated in 13 patients with chronic obstructive airways disease. Patients who had a normal Pco(2) despite severe airways obstruction retained relatively normal sensitivity to CO(2) as assessed by their "inspiratory mechanical work rate" response to CO(2). Others showed a raised Pco(2) in the presence of lesser degrees of airways obstruction and had reduced sensitivity to CO(2).

Arteries↗
PubMed1967

Oxygen therapy.

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Bronchitis↗
PubMed1966

Hypoxia in man.

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Alanine Transaminase↗
PubMed1965

Nevus angiolipomatosus vs focal dermal hypoplasia.

Widespread linear hamartoma of vascular, elastic, adipose, and connective tissue was observed in two girls with another and opposite defect, that of failure of development of focal areas of dermis. No abnormality in number or chromosones was found. Multiple associated defects of development of mesodermal and ectodermal tissues were present. The fat tissue appeared to be associated with vascular proliferation in the papillary bodies and to crowd out the corium by downward infiltration of newly developed fat. Elastic tissue fibers were demonstrable crossing between the fat cells and were prominent in the superficial dermis. There was a definite stratum of dermis dividing the superficial nevus fat and the normal subcutaneous fat. This evidence justifies the explanation of the superficial fat tumors as nevoid neoplasms rather than herniations of subcutaneous fat.

Abnormalities, Multiple↗
PubMedDate not supplied

Definition of the hyperventilation syndrome.

Delegates attending the Fourth International Symposium on Respiratory Psychophysiology indicated on a questionnaire those features of personality and mental disorders, symptoms, signs and measurements which they felt to be essential, closely associated, occasionally associated or irrelevant in the diagnosis of the hyperventilation syndrome (HVS). They also supplied their own definition of the HVS. Anxiety, symptoms reproduced in whole or in part by voluntary hyperventilation, breathlessness, hyperventilation and low CO2 were the features from the questionnaire most commonly considered to be essential in the diagnosis of the HVS. Delegates used the following phrases most frequently in their own definitions: "a variety of somatic symptoms", "hyperventilation", "associated low PCO2", "no organic disease" and "physiologically inappropriate". A consensus definition might read "the hyperventilation syndrome is a syndrome characterized by a variety of somatic symptoms induced by physiologically inappropriate hyperventilation and usually reproduced in whole or in part by voluntary hyperventilation". But for practical use, the nature of the symptoms and any other relevant features need to be clearly identified if this diagnosis is to be entertained in the course of a clinical consultation. This definition still lacks the qualities which are essential for an operational definition.

Health Occupations↗